Zebrafish embryos as a screen for DNA methylation modifications after compound exposure

MC Bouwmeester, S Ruiter, T Lommelaars… - Toxicology and applied …, 2016 - Elsevier
… In this study, we examined the applicability of the zebrafish embryo as a screening model
for DNA methylation modifications. Embryos were exposed from 0 to 72 h post fertilization (hpf) …

Genome-wide DNA methylation profiling in zebrafish

PJ Murphy, BR Cairns - Methods in Cell Biology, 2016 - Elsevier
Genomic DNA methylation functions to repress gene … contribution of regulated DNA
methylation to embryonic pluripotency, … in dynamic DNA methylation are conserved in zebrafish, …

[HTML][HTML] Associations between behavioral effects of bisphenol A and DNA methylation in zebrafish embryos

PA Olsvik, P Whatmore, SJ Penglase… - Frontiers in …, 2019 - frontiersin.org
… in the embryos. To improve the chances of finding significant DNA methylation effects we …
) was used to identify methylated genomic regions with whole-genome bisulfite sequencing (…

DNA methylation and gene expression alterations in zebrafish embryos exposed to cadmium

X Bian, Y Gao - Environmental Science and Pollution Research, 2021 - Springer
DNA methylation level of zebrafish embryo, and we observed global methylation and signaling
pathway-related gene DNAgene that causes DNA methylation changes in Cd and the …

DNA methylation dynamics during epigenetic reprogramming of medaka embryo

X Wang, RK Bhandari - Epigenetics, 2019 - Taylor & Francis
… and the maternal genome is reprogrammed in a pattern … we show DNA methylation
dynamics in medaka embryos, the … to mammalian genome methylation but not to zebrafish. The …

Embryonic exposure to benzo (a) pyrene inhibits reproductive capability in adult female zebrafish and correlation with DNA methylation

D Gao, J Lin, K Ou, Y Chen, H Li, Q Dai, Z Yu… - Environmental …, 2018 - Elsevier
… exposure causes changes in DNA methylation. Exposure of 2.5–96 hpf zebrafish embryos
to waterborne 24 μg/L BaP significantly decreased the global cytosine methylation by 44.8% (…

DNA methylation and gene expression alterations in zebrafish early-life stages exposed to the antibacterial agent triclosan

E Falisse, B Ducos, PA Stockwell, IM Morison… - Environmental …, 2018 - Elsevier
… , particularly during embryogenesis when DNA methylation patterns are being established.
… on DNA methylation and its correlation with gene expression, zebrafish embryos were …

Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling

Y Chernyavskaya, R Mudbhary, C Zhang… - …, 2017 - journals.biologists.com
genomic DNA from whole embryos contains cells with varying amounts of DNA methylation
and thus the genomic DNA … To test this, Tg(mpeg:mCherry) embryos were injected with either …

DNA methylation and the preservation of cell identity

O Bogdanović, R Lister - Current opinion in genetics & development, 2017 - Elsevier
… of embryonic development. Nevertheless, targeted deposition and removal of DNA methylation
… In zebrafish and mouse embryos, the loss of TET proteins results in severe gastrulation …

Variant Histone H2afv reprograms DNA methylation during early zebrafish development

B Madakashira, L Corbett, C Zhang, P Paoli… - Epigenetics, 2017 - Taylor & Francis
… We find that, in control embryos, bulk genome methylation decreases after gastrulation, with
… , total DNA methylation levels return to those detected in gastrula. Early zebrafish embryos