An introduction to epigenetic mechanisms
EJ Radford - Progress in molecular biology and translational …, 2018 - Elsevier
… a hierarchy of epigenetic … epigenetic mechanisms in this context. Neuronal activity has been
shown to result in dynamic changes in DNA methylation, 11 and there is evidence that DNA …
shown to result in dynamic changes in DNA methylation, 11 and there is evidence that DNA …
[HTML][HTML] Genome-wide DNA methylation profiling reveals novel epigenetic signatures in squamous cell lung cancer
YX Shi, Y Wang, X Li, W Zhang, HH Zhou, JY Yin… - BMC genomics, 2017 - Springer
… DNA methylation profiling on 24 LUSC and paired non-tumor lung (NTL) tissues by Illumina
Human Methylation … Moreover, hierarchical clustering analysis of the DNA methylation data …
Human Methylation … Moreover, hierarchical clustering analysis of the DNA methylation data …
[HTML][HTML] DNA methylation: Precise modulation of chromatin structure and dynamics
… DNA methylation plays a vital role in epigenetic regulation in both plants and animals,
and typically occurs at the 5-carbon position of the cytosine pyrimidine ring within the CpG …
and typically occurs at the 5-carbon position of the cytosine pyrimidine ring within the CpG …
[HTML][HTML] Universality of the DNA methylation codes in Eucaryotes
… Question arises if epigenetics provides just a set of … We argued that in the latter case the
epigenetic code should … data, and applied hierarchical clustering to identify methylation types in ~…
epigenetic code should … data, and applied hierarchical clustering to identify methylation types in ~…
The diverse roles of DNA methylation in mammalian development and disease
MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… Perhaps the hierarchical and highly regulated heterochromatization of the X chromosome
… is differentially established in the two parental germlines; these epigenetically imprinted …
… is differentially established in the two parental germlines; these epigenetically imprinted …
[HTML][HTML] Hierarchical deconvolution for extensive cell type resolution in the human brain using DNA methylation
… using a hierarchical modeling approach with differential DNA methylation patterns among
seven … related to pathobiological brain cell alteration and epigenetic regulation of the disease. …
seven … related to pathobiological brain cell alteration and epigenetic regulation of the disease. …
[HTML][HTML] Epigenetic machine learning: utilizing DNA methylation patterns to predict spastic cerebral palsy
EL Crowgey, AG Marsh, KG Robinson, SK Yeager… - BMC …, 2018 - Springer
… Assessing ∆ML score demonstrated a prevalence of altered methylation in 5’ UTR regions
for three of the hierarchical KEGG functional categories. Values plotted are means +/− SEM …
for three of the hierarchical KEGG functional categories. Values plotted are means +/− SEM …
[HTML][HTML] DNA methylation profiles capturing breast cancer heterogeneity
X Chen, J Zhang, X Dai - BMC genomics, 2019 - Springer
… As one of the most described epigenetic marks in human cancers, DNA methylation plays
… Purity of clusters obtained from hierarchical clustering using (d) pCpGs of GSE72245 on …
… Purity of clusters obtained from hierarchical clustering using (d) pCpGs of GSE72245 on …
Inference of Developmental Hierarchy and Functional States of Exhausted T Cells from Epigenetic Profiles with Deep Learning
… To quantify DNA methylation at the gene level, we calculated … Using DNA methylation
data, we rigorously screened for … miRNA, lncRNA, and DNA methylation data, highlighting the …
data, we rigorously screened for … miRNA, lncRNA, and DNA methylation data, highlighting the …
[HTML][HTML] Genome wide DNA methylation profiling identifies specific epigenetic features in high-risk cutaneous squamous cell carcinoma
D Hervás-Marín, F Higgins, O Sanmartín… - PLoS …, 2019 - journals.plos.org
… DNA methylation profile in human skin from pre- and post-malignant multistage cSCC
using the Infinium DNA Methylation … to the results of a hierarchical clustering algorithm. Z-score …
using the Infinium DNA Methylation … to the results of a hierarchical clustering algorithm. Z-score …
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