Exploring the evidence for epigenetic regulation of environmental influences on child health across generations

CV Breton, R Landon, LG Kahn, MB Enlow… - Communications …, 2021 - nature.com
… on child health in the Environmental influences on Child Health Outcomes (ECHO) study,
which will integrate the study of genetics and epigenetics with exposures and health outcomes …

Childhood adversity and epigenetic regulation of glucocorticoid signaling genes: Associations in children and adults

AR Tyrka, KK Ridout, SH Parade - Development and …, 2016 - cambridge.org
… Methylation, which is thought to be the most stable form of epigenetic change, is a likely …
to epigenetic regulation of genes involved in hypothalamus–pituitary–adrenal axis regulation, …

An investigation of child maltreatment and epigenetic mechanisms of mental and physical health risk

D Cicchetti, S Hetzel, FA Rogosch… - Development and …, 2016 - cambridge.org
… the effects of child abuse and neglect on methylation. Epigenetic regulation is a viable
candidate mechanism through which caregiving behaviors, including child maltreatment, may …

Epigenetic regulation of immune function in asthma

S Sharma, IV Yang, DA Schwartz - Journal of Allergy and Clinical …, 2022 - Elsevier
… between asthma and 3 key epigenetic processes that modify gene … epigenetic studies
focusing on immune regulation in asthma, we will discuss future directions for epigenetic

Epigenetic responses and the developmental origins of health and disease

D Goyal, SW Limesand, R Goyal - Journal of Endocrinology, 2019 - joe.bioscientifica.com
… silencing, and all are defined as epigenetic modifications. In the present review, we will
summarize the evidence supporting epigenetic regulation as a significant component in DOHaD. …

Intergenerational influences on child development: an epigenetic perspective

MJ Silver - … of Nutrition Challenges in Infants and Children, 2020 - karger.com
… of epigenetic mechanisms might influence the growth and development of children.
Nutritional and other environmental insults affecting parents could plausibly affect their children, …

Maternal and pediatric health and disease: integrating biopsychosocial models and epigenetics

LP Rubin - Pediatric research, 2016 - nature.com
… in health research, especially maternal child health (8,9). One underlying biological mechanism
for effects of fetal deprivation and stress is environmentally inducible epigenetic change (…

Epigenetic studies and pediatric research

JA Bellanti - Pediatric Research, 2020 - nature.com
… infants and children. In keeping with this mandate, this article reviews the subject of epigenetics,
which impacts pediatric research from bench to bedside. Epigenetic mechanisms exert …

Prenatal maternal stress and wheeze in children: novel insights into epigenetic regulation

S Trump, M Bieg, Z Gu, L Thürmann, T Bauer… - Scientific reports, 2016 - nature.com
children of highly stressed mothers. We were particularly interested in changes of the epigenetic
… the adverse respiratory outcome observed in children. Since calcium homeostasis and …

The effects of childhood maltreatment on epigenetic regulation of stress-response associated genes: An intergenerational approach

L Ramo-Fernández, C Boeck, AM Koenig, K Schury… - Scientific reports, 2019 - nature.com
… no effect on NR3C1 epigenetic regulation, it influenced … childhood might persistently (re)program
central signaling cascades that influence immune functions. The observed epigenetic