[HTML][HTML] Integration of epigenetic mechanisms into non-genotoxic carcinogenicity hazard assessment: Focus on DNA methylation and histone modifications

D Desaulniers, P Vasseur, A Jacobs… - International Journal of …, 2021 - mdpi.com
… Deregulated expression of any of 25 epigenetic toxicity pathway components (SET1,
MLL1, … of the receptor tyrosine kinase-extracellular signal-regulated kinase signaling (RTK-ERK) …

[HTML][HTML] A Tox21 approach to altered epigenetic landscapes: assessing epigenetic toxicity pathways leading to altered gene expression and oncogenic transformation …

CL Parfett, D Desaulniers - International journal of molecular sciences, 2017 - mdpi.com
… shows that disruption of epigenetic processes by chemicals … and readers) that convey the
epigenetic information. Evidence is … induce toxicity through disturbance of functional epigenetic

[HTML][HTML] Immunotoxicity, genotoxicity and epigenetic toxicity of nanomaterials: New strategies for toxicity testing?

M Dusinska, J Tulinska, N El Yamani… - … Chemical Toxicology, 2017 - Elsevier
… However, to initiate epigenetic toxicity screens for NM exposure, … , epigenetic changes and
adverse phenotypic endpoints, and to develop improved assays to monitor epigenetic toxicity. …

Methoxychlor and vinclozolin induce rapid changes in intercellular and intracellular signaling in liver progenitor cells

P Babica, R Zurabian, ER Kumar, R Chopra… - Toxicological …, 2016 - academic.oup.com
… genomic signaling. Such alterations of rapid intercellular and intracellular signaling events
… , could also contribute to transgenerational epigenetic effects of endocrine disruptors. …

Progress in identifying epigenetic mechanisms of xenobiotic-induced non-genotoxic carcinogenesis

R Terranova, A Vitobello, ADR Espinola… - … Opinion in Toxicology, 2017 - Elsevier
… Enhancers are bound by regulatory transcription factors and integrate extracellular signalling
pathways with intracellular cell fate information to elicit cell type-specific transcriptional …

Epigenetic effects induced by methamphetamine and methamphetamine‐dependent oxidative stress

F Limanaqi, S Gambardella, F Biagioni… - Oxidative medicine …, 2018 - Wiley Online Library
… into epigenetic events, which are derived from the translation of postsynaptic noncanonical
signaling … In the present section, we wish to mention that METH produces presynaptic toxicity

Epigenetic modulations in nanoparticle-mediated toxicity

BSE Wong, Q Hu, GH Baeg - Food and Chemical Toxicology, 2017 - Elsevier
… is that NP exposure has affected the epigenetic prints in these offspring. Here, we discussed
about the NP-mediated epigenetic modifications in the aspects of DNA methylation, histone …

Regulation of cytochrome P450 expression by microRNAs and long noncoding RNAs: Epigenetic mechanisms in environmental toxicology and carcinogenesis

D Li, WH Tolleson, D Yu, S Chen, L Guo… - … Science and Health …, 2019 - Taylor & Francis
signaling pathways associated with cell cycle arrest, apoptosis, cell proliferation, and survival
in ways that can mediate xenobiotic toxicity… of expression influence toxicity. While some …

[HTML][HTML] Epigenetic aspects of engineered nanomaterials: is the collateral damage inevitable?

MR Gedda, PK Babele, K Zahra… - … in Bioengineering and …, 2019 - frontiersin.org
… of epigenetic toxicity potential … signaling, apoptosis and trigger inflammation epigenetic
alteration and modifications in the chromosome. Among various toxicity mechanisms, epigenetic

[HTML][HTML] Epigenetic effects of nanomaterials and nanoparticles

M Pogribna, G Hammons - Journal of Nanobiotechnology, 2021 - Springer
… Furthermore, most of the current studies in the field of epigenetic toxicology have focused
on the epigenetic effects of overall NMs and NPs exposure without taking into consideration …