Epigenetics in Alzheimer's disease: perspective of DNA methylation

TJ Qazi, Z Quan, A Mir, H Qing - Molecular Neurobiology, 2018 - Springer
… role of epigenetic factors in developing neurological disorders in … epigenetic mechanisms
especially the DNA methylation in Alzheimer’s disease (AD), late-onset Alzheimer’s disease

DNA methylation in the pathology of Alzheimer's disease: from gene to cognition

CH Poon, LSR Tse, LW Lim - Annals of the New York Academy …, 2020 - Wiley Online Library
… conflicting observations from AD research and its pivotal role in … of DNA methylation, the
effects of aberrant methylation on gene … , as well as memory epigenetics in Alzheimer's disease. …

Epigenetics of Alzheimer's disease

M Nikolac Perkovic, A Videtic Paska, M Konjevod… - Biomolecules, 2021 - mdpi.com
… Since a similar situation applies for epigenetics, in our review we mainly inspected studies
which analyzed DNA methylation on a genome-wide basis, enabling a broader view of the …

DNA methylation in Alzheimer's disease: In brain and peripheral blood

X Wei, L Zhang, Y Zeng - Mechanisms of Ageing and Development, 2020 - Elsevier
Alzheimer's disease (AD) is the most widespread … categories of epigenetic processes:
DNA methylation and … DNA methylation is a vital component of the epigenetic machinery that …

Epigenetics: Recent advances and its role in the treatment of Alzheimer's disease

X Xiao, X Liu, B Jiao - Frontiers in Neurology, 2020 - frontiersin.org
… recent studies of epigenetics in AD, including DNA methylation/hydroxymethylation, histone
… of global DNA methylation/hydroxymethylation in AD. Epigenetic genome-wide association

[PDF][PDF] DNA methylation alterations in Alzheimer's disease

AS Yokoyama, JC Rutledge… - Environmental epigenetics, 2017 - academic.oup.com
epigenetics is a broad term encompassing DNA methylation, histone modifications and
non-coding RNA, this review will focus specifically on DNA methylationAlzheimer disease. Arch …

DNA methylation: a promising approach in management of Alzheimer's disease and other neurodegenerative disorders

G Kaur, SSS Rathod, MM Ghoneim, S Alshehri… - Biology, 2022 - mdpi.com
DNA methylation appears as one of the important epigenetic modifications which not …
diseases, such as Alzheimer’s disease. The present work focuses on the history of DNA methylation

Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease

AR Smith, RG Smith, E Pishva, E Hannon… - … epigenetics, 2019 - Springer
association study of both DNA methylation and hydroxymethylation in Alzheimer’s disease
… estimates of DNA hypermethylation in ANK1 in Alzheimer’s disease were underestimates …

[HTML][HTML] Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer's disease

DL McCartney, AJ Stevenson, RM Walker… - Alzheimer's & Dementia …, 2018 - Elsevier
… “epigenetic clock” is a DNA methylation–based estimate of biological age and is correlated
with chronological age—the greatest risk factor for Alzheimer's disease (… the epigenetic clock …

Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer's disease

CT Watson, P Roussos, P Garg, DJ Ho, N Azam… - Genome medicine, 2016 - Springer
… We performed a genome-wide screen of DNA methylation … temporal gyrus of patients
with Alzheimer’s disease and non-… Alzheimer’s disease-associated differentially methylated