… , it will be important to attribute mechanisms to the identified mutations so we might further
understand these EBV-associated cancers and their evolution to treat them more effectively. …

… For many years, the standard treatment for locally advanced NPC involved radiation therapy
… Subsequently, clinical practice quickly evolved toward concurrent chemoradiation therapy …

… It is more than 50 years since the Epstein–Barr virus (EBV), the first human tumour virus,
was … insights at the molecular level in the diagnosis, treatment and prevention of cancer. …

Introduction: Epstein–Barr virus (EBV) infects more than 95% of the world’s population and
is associated with infectious mononucleosis as well as a number of cancers in various …

… treatment of cancers. Adoptive T-cell therapy has been successfully used in the prevention
and treatment … EBV reactivation, termed PTLD that can evolve into Hodgkin lymphoma or non-…

… , including drugs licensed for treatment of other herpesviruses, … EBV proteins, Epstein-Barr
nuclear antigens EBNA3, EBNA4 … But how they arise and evolve during primary EBV infection …

… demonstrating a link between B cell-tropic Epstein–Barr virus (EBV) and disease onset.
Efforts to develop antiviral strategies for treating MS are underway. Although gaps remain in our …

… to start treatment before these conditions develop. At present, the only effective treatment …
reported that CAEBV patients showed clonal evolution of the infected cells and eventually …

… for recognizing and identifying early and effective treatments at different stages in the …
The fact that EBV persists for the lifetime of the host indicates that it has evolved successful …

… treatments. Multiple aetiological factors have been described including environmental factors,
genetics, and viral factors (Epstein Barr Virus, EBV), making NPC treatment that … evolution …