Low-dose erlotinib treatment in elderly or frail patients with EGFR mutation–positive non–small cell lung cancer: A multicenter phase 2 trial

S Miyamoto, K Azuma, H Ishii, A Bessho… - JAMA …, 2020 - jamanetwork.com
… Based on the rationales, we hypothesized that low-dose erlotinib would be safe and …
multicenter phase 2 clinical trial to investigate the efficacy and safety of low-dose erlotinib in …

… treatment of patients with EGFR wild-type advanced non-small-cell lung cancer (ECOG-ACRIN 1512): a randomised, controlled, open-label, multicentre, phase 2 trial

JW Neal, SE Dahlberg, HA Wakelee, SC Aisner… - The Lancet …, 2016 - thelancet.com
… patients to erlotinib treatment, 40 patients to cabozantinib treatment, and … erlotinib in wild-type
EGFR NSCLC formed the basis for the selection of the erlotinib control group in this study

A multicenter phase II study of sorafenib in combination with erlotinib in patients with advanced non-small cell lung cancer (KCSG-0806)

SM Lim, BC Cho, SW Kim, SY Kang, DS Heo, HT Kim… - Lung cancer, 2016 - Elsevier
… Sorafenib and erlotinib are potent, orally administered receptor tyrosine kinase inhibitors …
a phase II study to determine the clinical activity of sorafenib in combination with erlotinib in …

… in patients with EGFR-positive advanced non-squamous non-small-cell lung cancer (NEJ026): interim analysis of an open-label, randomised, multicentre, phase 3 trial

H Saito, T Fukuhara, N Furuya, K Watanabe… - The Lancet …, 2019 - thelancet.com
… , 2018, for clinical trials published in English using the search terms “erlotinib”, “bevacizumab”…
phase 2 trials that assessed the activity of erlotinib plus bevacizumab as first-line treatment

… therapy in unresectable stage III epidermal growth factor receptor mutation-positive non-small cell lung cancer: a multicenter, randomized, open-label, phase 2 trial

L Xing, G Wu, L Wang, J Li, J Wang, Z Yuan… - International Journal of …, 2021 - Elsevier
… However, these trials were performed in unselected patients without EGFR … phase 2 trial
has compared erlotinib + RT and CCRT in patients with EGFRm-positive unresectable stage III …

… with advanced, metastatic, EGFR-mutant non-small-cell lung cancer (NEJ026): overall survival analysis of an open-label, randomised, multicentre, phase 3 trial

Y Kawashima, T Fukuhara, H Saito… - The Lancet …, 2022 - thelancet.com
study was a randomised, multicentre, phase 2 trial that compared bevacizumab–erlotinib
with erlotinib alone as first-line treatments in 154 … In the JO25567 study, bevacizumab–erlotinib

A randomized Phase 2 study to compare erlotinib with or without bevacizumab in previously untreated patients with advanced non–small cell lung cancer with EGFR …

Y Lee, HR Kim, MH Hong, KH Lee, KU Park, GK Lee… - Cancer, 2023 - Wiley Online Library
… , multicenter, randomized Phase 2 study in South Korea. Chemonaïve patients with Stage
… Asymptomatic brain metastasis (BM) was enrolled without local treatment. Patients received …

Randomized phase II study of fulvestrant and erlotinib compared with erlotinib alone in patients with advanced or metastatic non-small cell lung cancer

EB Garon, JM Siegfried, LP Stabile, PA Young… - Lung Cancer, 2018 - Elsevier
multicenter, randomized, open-label phase II trial compared the objective response rate (ORR)
as defined by RECIST 1.0 in the erlotinib plus fulvestrant arm versus erlotinib2:1 by a …

A phase II randomized trial of panitumumab, erlotinib, and gemcitabine versus erlotinib and gemcitabine in patients with untreated, metastatic pancreatic …

TR Halfdanarson, NR Foster, GP Kim, JP Meyers… - The …, 2019 - academic.oup.com
… a randomized phase II trial, evaluating the efficacy of a combined EGFR inhibition using
erlotinib and panitumumab in conjunction with gemcitabine with gemcitabine plus erlotinib as a …

… bevacizumab in patients with advanced non-small-cell lung cancer and activating EGFR mutations (BELIEF): an international, multicentre, single-arm, phase 2 trial

R Rosell, U Dafni, E Felip… - The Lancet …, 2017 - thelancet.com
Study design and participants BELIEF was an international, multicentre, single-arm,
phase 2 trial to test the efficacy of the combination of erlotinib and bevacizumab in treatment-naive …