Estrogen receptor beta as target for colorectal cancer prevention
… studies indicates that expression of the estrogen receptor beta (ERβ/ESR2) demonstrates
an inverse relationship with the presence of colorectal polyps and stage of tumors, and can …
an inverse relationship with the presence of colorectal polyps and stage of tumors, and can …
Combined estrogen alpha and beta receptor expression has a prognostic significance for colorectal cancer patients
… We reported that high estrogen receptor beta (ERβ) expression is independently associated
… colorectal cancer (CRC) patients. However, estrogen receptor alpha (ERα) is expressed at …
… colorectal cancer (CRC) patients. However, estrogen receptor alpha (ERα) is expressed at …
High expression of estrogen-related receptor α is significantly associated with poor prognosis in patients with colorectal cancer
R Liang, Y Lin, CL Yuan, ZH Liu, YQ Li… - Oncology …, 2018 - spandidos-publications.com
… orphan receptor, which is associated with estrogen receptor α. … cancer tissues and 127
adjacent normal tissues, respectively. The number of ERRα high expression colorectal cancer (…
adjacent normal tissues, respectively. The number of ERRα high expression colorectal cancer (…
Positive expression of estrogen receptor alpha correlates with poor prognosis and metastasis in colorectal cancer
G Topi, SR Satapathy, RR Ehrnström, ML Lydrup… - Cancer Research, 2020 - AACR
… receptor in the normal colon mucosa, and its expression is downregulated in colorectal
cancer (CRC). On the other hand, ER alpha (ERα) is very little expressed in the normal colon …
cancer (CRC). On the other hand, ER alpha (ERα) is very little expressed in the normal colon …
Targeting estrogen receptors in colorectal cancer
JW Maingi, S Tang, S Liu, W Ngenya, E Bao - Molecular Biology Reports, 2020 - Springer
… Abnormal estrogen receptor signaling may increase the risk of development of a variety of
diseases including colorectal cancer (CRC). Estrogen receptor beta (ERβ) is the predominant …
diseases including colorectal cancer (CRC). Estrogen receptor beta (ERβ) is the predominant …
Estrogen concentration and estrogen receptor-β expression in postmenopausal colon cancer considering patient/tumor background
N Honma, T Arai, Y Matsuda, Y Fukunaga… - Journal of Cancer …, 2022 - Springer
… A large number of studies have suggested an inhibitory role of estrogens against colorectal
cancer (CRC), but persistent controversy exists. CRC characteristics are affected by sex, age…
cancer (CRC), but persistent controversy exists. CRC characteristics are affected by sex, age…
Colitis‐induced colorectal cancer and intestinal epithelial estrogen receptor beta impact gut microbiota diversity
A Ibrahim, LW Hugerth, L Hases… - … journal of cancer, 2019 - Wiley Online Library
… to colorectal carcinogenesis, studies have characterized microbiota diversity in individuals
with colorectal cancer.9… Further, estrogen through estrogen receptor β (ERβ/ESR2) appears to …
with colorectal cancer.9… Further, estrogen through estrogen receptor β (ERβ/ESR2) appears to …
Estrogen receptors in colorectal cancer: Facts, novelties and perspectives
I Ditonno, G Losurdo, M Rendina, M Pricci, B Girardi… - Current …, 2021 - mdpi.com
… To date, there is no evidence available showing an association between estrogen receptors
and colitis-associated cancer, but some data in murine models suggest a potential role. …
and colitis-associated cancer, but some data in murine models suggest a potential role. …
Nuclear receptor estrogen-related receptor gamma suppresses colorectal cancer aggressiveness by regulating Wnt/β-catenin signaling
X Guo, L Yue, M Li, A Dai, J Sun, L Fang… - …, 2022 - academic.oup.com
… gamma (ESRRG), the NR3B subfamily of nuclear receptors, is characterized by a significant
homology similarity with the classical estrogen receptors at the amino acid level, and is …
homology similarity with the classical estrogen receptors at the amino acid level, and is …
[HTML][HTML] Estrogen receptor β affects hypoxia response in colorectal cancer cells
AA Rawłuszko-Wieczorek, J Lipowicz… - … et Biophysica Acta (BBA …, 2024 - Elsevier
… In summary, estrogen receptor β has recently received more interest as a promising targeted
therapy for colorectal cancer, as it affects multiple pathways and the expression of a wide …
therapy for colorectal cancer, as it affects multiple pathways and the expression of a wide …
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