Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment
C Zhong, K Cui, C Wilhelm, G Hu, K Mao… - Nature …, 2016 - nature.com
… The transcription factor GATA-3 is indispensable for the development of all … low GATA-3
expression in committed group 3 ILCs (ILC3 cells) has not been identified. We found that GATA-3 …
expression in committed group 3 ILCs (ILC3 cells) has not been identified. We found that GATA-3 …
GATA transcription factors in development and disease
M Tremblay, O Sanchez-Ferras, M Bouchard - Development, 2018 - journals.biologists.com
… The GATA family of proteins. (A) The six murine members of the GATA family of transcription
factors are grouped as GATA1/2/3 and GATA4/5/6 based on expression and similarity. They …
factors are grouped as GATA1/2/3 and GATA4/5/6 based on expression and similarity. They …
[HTML][HTML] Interaction of the pioneer transcription factor GATA3 with nucleosomes
H Tanaka, Y Takizawa, M Takaku, D Kato… - Nature …, 2020 - nature.com
… of transcription factors, termed pioneer transcription factors, has … The GATA family of proteins
are zinc finger transcription factors … , including mammary epithelial cell differentiation 3,4,5 . …
are zinc finger transcription factors … , including mammary epithelial cell differentiation 3,4,5 . …
[HTML][HTML] Differential expression of the transcription factor GATA3 specifies lineage and functions of innate lymphoid cells
… by the expression of the transcription factor PLZF. Here, we examined transcription factor(s) …
Conditional deletion of Gata3 resulted in the loss of PLZF + non-LTi progenitors but not the …
Conditional deletion of Gata3 resulted in the loss of PLZF + non-LTi progenitors but not the …
Transcription factors directing Th2 differentiation: Gata-3 plays a dominant role
A O'Garra, L Gabryšová - The Journal of Immunology, 2016 - journals.aai.org
… confirming that GATA-3 is the key transcription factor regulating … showed that the transcription
factor GATA-3 was upregulated … importance of this transcription factor in Th2 differentiation (…
factor GATA-3 was upregulated … importance of this transcription factor in Th2 differentiation (…
Role of GATA3 in tumor diagnosis: A review
MK Najafabadi, E Mirzaeian, SM Montazerin… - … -Research and Practice, 2021 - Elsevier
… GATA binding protein 3 (GATA3) belongs to a family of transcription factors comprising six
members. These proteins identify GATA containing sequences in the target gene and bind to …
members. These proteins identify GATA containing sequences in the target gene and bind to …
[HTML][HTML] GATA3 immunoreactivity expands the transcription factor profile of pituitary neuroendocrine tumors
… This study shows that GATA3 … pattern of transcription factors that are used to classify
adenohypophysial tumors and is important in the differential diagnosis of sellar tumors, as GATA3 …
adenohypophysial tumors and is important in the differential diagnosis of sellar tumors, as GATA3 …
GATA transcription factors: basic principles and related human disorders
T Fujiwara - The Tohoku journal of experimental medicine, 2017 - jstage.jst.go.jp
… to gain novel insights into factors involved in the regulation of GATA-2 expression. We
screened 995 transcription factor genes and found that CITED2 acted as a GATA-2 activator in …
screened 995 transcription factor genes and found that CITED2 acted as a GATA-2 activator in …
The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression
F Zhang, H Tang, Y Jiang, Z Mao - Oncogene, 2017 - nature.com
… Here, we report that GATA3, through its activity as a transcription factor regulating CtIP
expression, is required for DNA DSB repair by HR. Loss of GATA3 greatly impairs the expression …
expression, is required for DNA DSB repair by HR. Loss of GATA3 greatly impairs the expression …
Utility of GATA-3 expression in the analysis of pituitary neuroendocrine tumour (PitNET) transcription factors
… that GATA-3 IHC … the transcription factors, despite having all the morphological hallmarks
of a PitNET. Hence, we sort to demonstrate the utility of GATA-3 IHC as a transcription factor in …
of a PitNET. Hence, we sort to demonstrate the utility of GATA-3 IHC as a transcription factor in …
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