Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment

C Zhong, K Cui, C Wilhelm, G Hu, K Mao… - Nature …, 2016 - nature.com
… The transcription factor GATA-3 is indispensable for the development of all … low GATA-3
expression in committed group 3 ILCs (ILC3 cells) has not been identified. We found that GATA-3

GATA transcription factors in development and disease

M Tremblay, O Sanchez-Ferras, M Bouchard - Development, 2018 - journals.biologists.com
… The GATA family of proteins. (A) The six murine members of the GATA family of transcription
factors are grouped as GATA1/2/3 and GATA4/5/6 based on expression and similarity. They …

[HTML][HTML] Interaction of the pioneer transcription factor GATA3 with nucleosomes

H Tanaka, Y Takizawa, M Takaku, D Kato… - Nature …, 2020 - nature.com
… of transcription factors, termed pioneer transcription factors, has … The GATA family of proteins
are zinc finger transcription factors … , including mammary epithelial cell differentiation 3,4,5 . …

[HTML][HTML] Differential expression of the transcription factor GATA3 specifies lineage and functions of innate lymphoid cells

C Zhong, M Zheng, K Cui, AJ Martins, G Hu, D Li… - Immunity, 2020 - cell.com
… by the expression of the transcription factor PLZF. Here, we examined transcription factor(s) …
Conditional deletion of Gata3 resulted in the loss of PLZF + non-LTi progenitors but not the …

Transcription factors directing Th2 differentiation: Gata-3 plays a dominant role

A O'Garra, L Gabryšová - The Journal of Immunology, 2016 - journals.aai.org
… confirming that GATA-3 is the key transcription factor regulating … showed that the transcription
factor GATA-3 was upregulated … importance of this transcription factor in Th2 differentiation (…

Role of GATA3 in tumor diagnosis: A review

MK Najafabadi, E Mirzaeian, SM Montazerin… - … -Research and Practice, 2021 - Elsevier
GATA binding protein 3 (GATA3) belongs to a family of transcription factors comprising six
members. These proteins identify GATA containing sequences in the target gene and bind to …

[HTML][HTML] GATA3 immunoreactivity expands the transcription factor profile of pituitary neuroendocrine tumors

O Mete, M Kefeli, S Çalışkan, SL Asa - Modern Pathology, 2019 - Elsevier
… This study shows that GATA3 … pattern of transcription factors that are used to classify
adenohypophysial tumors and is important in the differential diagnosis of sellar tumors, as GATA3

GATA transcription factors: basic principles and related human disorders

T Fujiwara - The Tohoku journal of experimental medicine, 2017 - jstage.jst.go.jp
… to gain novel insights into factors involved in the regulation of GATA-2 expression. We
screened 995 transcription factor genes and found that CITED2 acted as a GATA-2 activator in …

The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression

F Zhang, H Tang, Y Jiang, Z Mao - Oncogene, 2017 - nature.com
… Here, we report that GATA3, through its activity as a transcription factor regulating CtIP
expression, is required for DNA DSB repair by HR. Loss of GATA3 greatly impairs the expression …

Utility of GATA-3 expression in the analysis of pituitary neuroendocrine tumour (PitNET) transcription factors

J Turchini, L Sioson, A Clarkson, A Sheen, AJ Gill - Endocrine Pathology, 2020 - Springer
… that GATA-3 IHC … the transcription factors, despite having all the morphological hallmarks
of a PitNET. Hence, we sort to demonstrate the utility of GATA-3 IHC as a transcription factor in …