[HTML][HTML] Rare epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer

PT Harrison, S Vyse, PH Huang - Seminars in cancer biology, 2020 - Elsevier
… Epidermal growth factor receptor (EGFR) mutations are the second most common oncogenic
driver event in non-small cell lung cancer (NSCLC). Classical activating mutations (exon 19 …

A review on epidermal growth factor receptor's role in breast and non-small cell lung cancer

V Subramaniyan, S Fuloria, G Gupta, DH Kumar… - Chemico-biological …, 2022 - Elsevier
transcription factor translocation and DNA transcription via … via cell surface receptors for
growth factors (GFs). This pathway is particularly important for EGF and fibroblast growth factor (…

Worldwide prevalence of epidermal growth factor receptor mutations in non-small cell lung cancer: a meta-analysis

B Melosky, K Kambartel, M Haentschel… - Molecular Diagnosis & …, 2022 - Springer
… Identification of variable epidermal growth factor receptor (EGFR) gene mutations in non-small
cell lung cancer (NSCLC) is important for the selection of appropriate targeted therapies. …

[HTML][HTML] Role of epidermal growth factor receptor in lung cancer and targeted therapies

TC Liu, X Jin, Y Wang, K Wang - American Journal of Cancer …, 2017 - ncbi.nlm.nih.gov
… In the current review, we propose to illustrate the role of EGFR group of growth factors in lung
cancer progression and metastasis. We will particularly emphasize upon the impact of well-…

Immune checkpoint inhibitors in epidermal growth factor receptor mutant non-small cell lung cancer: Current controversies and future directions

RA Soo, SM Lim, NL Syn, R Teng, R Soong, TSK Mok… - Lung Cancer, 2018 - Elsevier
… Major advances with the development of epidermal growth factor receptor tyrosine kinase
inhibitors and immune check-point inhibitors have ushered in a new era in lung cancer therapy…

First‐line treatment of advanced epidermal growth factor receptor (EGFR) mutation positive non‐squamous non‐small cell lung cancer

J Greenhalgh, A Boland, V Bates… - Cochrane Database …, 2021 - cochranelibrary.com
… type of lung cancer is non‐small cell lung cancer (NSCLC). … kind of cancer known as epidermal
growth factor receptor … in the cancer cells to the genes controlling tumour growth. In this …

Epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC)

C O'Leary, H Gasper, KB Sahin, M Tang, A Kulasinghe… - Pharmaceuticals, 2020 - mdpi.com
… Vascular endothelial growth factor (VEGF) in lung cancer is considered an attractive
target for therapy due to the role this pathway plays in lung cancer growth and progression [63]. …

Efficacy and safety of first line treatments for patients with advanced epidermal growth factor receptor mutated, non-small cell lung cancer: systematic review and …

YI Zhao, J Liu, X Cai, Z Pan, J Liu, W Yin, H Chen, Z Xie… - Bmj, 2019 - bmj.com
… outcomes of treatments in different groups of patients with advanced epidermal growth factor
receptor (egfr) mutated non-small cell lung cancer (nsclc). (a) comparisons on progression …

Hepatocyte growth factor produced in lung fibroblasts enhances non-small cell lung cancer cell survival and tumor progression

N Kanaji, M Yokohira, Y Nakano-Narusawa… - Respiratory …, 2017 - Springer
… and its impact on lung cancer progression. We found that HGF production … lung fibroblasts
was stimulated by lung cancer cells and that HGF promoted the survival of lung cancer cells. …

Epidermal growth factor receptor mutation enhances expression of vascular endothelial growth factor in lung cancer

MS Hung, IC Chen, PY Lin, JH Lung… - Oncology …, 2016 - spandidos-publications.com
… to have a critical role in tumor angiogenesis. In the present study, the … growth factor (VEGF)
was investigated in lung cancer cell lines and non‑small‑cell lung cancer (NSCLC) tumor