[HTML][HTML] Mechanisms of resistance to anti-epidermal growth factor receptor inhibitors in metastatic colorectal cancer

V Sforza, E Martinelli, F Ciardiello… - World journal of …, 2016 - ncbi.nlm.nih.gov
… Epidermal growth factor receptor and its downstream signaling pathway. Binding of ligands
such as epidermal growth factor (EGF) to Epidermal growth factor receptor (EGFR) activates …

Epidermal growth factor receptor inhibitors as potential anticancer agents: An update of recent progress

B Sharma, VJ Singh, PA Chawla - Bioorganic Chemistry, 2021 - Elsevier
… Epidermal growth factor receptor (EGFR) is a vital intermediate in cell signaling pathway …
Here, we have discussed anti-cancer activity and growth factor receptor inhibitory activity …

[HTML][HTML] Recent progress on vascular endothelial growth factor receptor inhibitors with dual targeting capabilities for tumor therapy

Y Liu, Y Li, Y Wang, C Lin, D Zhang, J Chen… - Journal of Hematology & …, 2022 - Springer
… Vascular endothelial growth factor receptors (VEGFRs) are a family of receptorinhibitors
have been widely used in the treatment of various tumors. However, current VEGFR inhibitors

Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition

AN Hata, MJ Niederst, HL Archibald… - Nature medicine, 2016 - nature.com
growth factor receptor (EGFR)-mutant non-small-cell lung cancers to EGFR inhibitors have
… to third-generation EGFR inhibitors that target EGFR T790M ; treatment with navitoclax, an …

Recent advances in epidermal growth factor receptor inhibitors (EGFRIs) and their role in the treatment of cancer: a review

A Unnisa, AK Chettupalli, T Hussain… - Anti-Cancer Agents in …, 2022 - ingentaconnect.com
… Woodburn, JR The epidermal growth factor receptor and its … epidermal growth factor receptor
(EGFR) inhibitors against … Epidermal growth factor receptor inhibitors in cancer treatment: …

Adverse kidney effects of epidermal growth factor receptor inhibitors

H Izzedine, MA Perazella - Nephrology Dialysis Transplantation, 2017 - academic.oup.com
… -kDa type I transmembrane growth factor receptor located on the short arm of chromosome
7 [1]. As seen in Figure 1, EGFR binds to multiple ligands [EGF, transforming growth factor-α (…

[HTML][HTML] Repurposed anti-cancer epidermal growth factor receptor inhibitors: mechanisms of neuroprotective effects in Alzheimer's disease

HM Mansour, HM Fawzy, AS El-Khatib… - Neural regeneration …, 2022 - journals.lww.com
growth factor modulation. Finally, we will discuss future perspectives and under-examined
epidermal growth factor receptor … We conclude that epidermal growth factor receptor inhibitors

Dermatologic adverse events associated with selective fibroblast growth factor receptor inhibitors: overview, prevention, and management guidelines

ME Lacouture, V Sibaud, MJ Anadkat… - The …, 2021 - academic.oup.com
… Schematic representation of dermatologic adverse events associated with fibroblast growth
factor receptor inhibition. Suggested dose modifications for dermatologic adverse events: …

Fibroblast growth factor receptor inhibitors: patent review (2015–2019)

G Marseglia, A Lodola, M Mor… - Expert Opinion on …, 2019 - Taylor & Francis
… Introduction: fibroblast growth factor receptors (FGFRs) are a family of tyrosine-kinase
receptors whose signaling cascade regulates cellular proliferation, differentiation, and survival. …

The incidence and management of cutaneous adverse events of the epidermal growth factor receptor inhibitors

W Owczarek, M Słowińska, A Lesiak… - … in Dermatology and …, 2017 - termedia.pl
… Third-generation epidermal growth factor receptor tyrosine kinase inhibitors in advanced
nonsmall cell lung cancer. … Epidermal growth factor receptor inhibitors: a review of cutaneous …