[HTML][HTML] Myocardial structure and functional alterations in a preclinical model of exertional heat stroke

CM Chao, LY Wang, CC Huang, WT Chang, LY Tang… - Life Sciences, 2023 - Elsevier
Aim Relatively little information is available about the effect of an acute exertional heat stroke
(EHS) on myocardium structure and function. Herein, we used a survival male rat model of …

[HTML][HTML] Heat stroke

T Hifumi, Y Kondo, K Shimizu, Y Miyake - Journal of intensive care, 2018 - Springer
Background Heat stroke is a life-threatening injury requiring neurocritical care; however,
heat stroke has not been completely examined due to several possible reasons, such as no …

Classic and exertional heatstroke

A Bouchama, B Abuyassin, C Lehe, O Laitano… - Nature Reviews …, 2022 - nature.com
… core body temperature and neurological alterations during heatwaves. Thus, if the patient
subsequently dies, death can be unambiguously attributed to heatstroke. However, difficulties …

Heatstroke

S Al Mahri, A Bouchama - Handbook of clinical neurology, 2018 - Elsevier
… patient with altered mental status during a heat wave or following vigorous muscle exertion.
Heat can damage the structure and function of essential … Brain damage after heat stroke

[HTML][HTML] The gastrointestinal exertional heat stroke paradigm: pathophysiology, assessment, severity, aetiology and nutritional countermeasures

HB Ogden, RB Child, JL Fallowfield, SK Delves… - Nutrients, 2020 - mdpi.com
alterations. Nutritional countermeasures to maintain GI barrier integrity following exertional-heat
… The focus of this review is to evaluate: (1) the GI paradigm of exertional heat stroke; (2) …

Exertional heat stroke leads to concurrent long‐term epigenetic memory, immunosuppression and altered heat shock response in female mice

KO Murray, JO Brant, JD Iwaniec… - The Journal of …, 2021 - Wiley Online Library
… exertional heat stroke (EHS) has been linked to increased susceptibility to a second heat
stroke… epigenetic and phenotypic consequences of exertional heat stroke. He is also involved in …

Neuromotor deficits and altered physiological responses to repeated exertional heat stroke exposures in mice

JM Alzahrani, KO Murray, BJ Gambino… - American Journal …, 2022 - journals.physiology.org
function at elevated temperature is the primary clinical symptom used to distinguish heat
stroke from other forms of less serious heat … rates seen in human heat stroke victims (16, 21). …

[HTML][HTML] Outcome and risk factors associated with extent of central nervous system injury due to exertional heat stroke

M Yang, Z Li, Y Zhao, F Zhou, Y Zhang, J Gao, T Yin… - Medicine, 2017 - journals.lww.com
… -ischemia, significant alterations in both neurologic function and cerebral histopathology are
… CNS has been manifested by a report of 3 heat stroke patients using cooling device. [38] By …

Delayed metabolic dysfunction in myocardium following exertional heat stroke in mice

O Laitano, CK Garcia, AJ Mattingly… - The Journal of …, 2020 - Wiley Online Library
Key points Exposure to exertional heat stroke (EHS) is associated with increased risk of long‐term
cardiovascular disorders in humans. We demonstrate that in female mice, severe EHS …

Exertional heat stroke causes long-term skeletal muscle epigenetic reprogramming, altered gene expression, and impaired satellite cell function in mice

KO Murray, JO Brant, RA Spradlin… - American Journal …, 2024 - journals.physiology.org
… significant clinical sequelae of heat stroke. Recently, 51 using a preclinical model of EHS,
our laboratory reported that in vivo neuromotor 52 function recovered completely within two …