Hepatocellular carcinoma (HCC) is a highly malignant tumor found in the bile duct epithelial
cells, and the second most common tumor of the liver. However, the pivotal roles of most …

… (ceRNA) network and have attracted growing attention. The present study explored the
regulatory mechanisms and functional roles of lncRNAs as ceRNAs in hepatocellular carcinoma (…

… d The flowchart shows the computational algorithm of our mathematical model to identify
dynamic network biomarkers (DNBs), signalling the pre-metastatic state. e The graph illustrates …

… and to construct dynamic networks. Dynamic concentration analysis and network topological
… 20:5 was identified as the potential biomarker for hepatocellular carcinoma (HCC). It can be …

… biomarkers in the early detection of hepatocellular carcinoma… Therefore, constructing a
network to analyze biomarkers … –gene interaction network for biomarker identification in HCC. …

… as a dominant hazard factor for hepatocellular carcinoma (HCC) and accounts for at least …
network (PPI) was performed. The ten hub genes screened out from the PPI network were …

… methods, the use of novel biomarkers, and the construction of … can be used to identify
biomarkers or networks of genes that are … We constructed a complex network in which genes …

… , and may be regarded as a valuable biomarker for diagnosis, treatment and prognosis of
tumors (40–42). In the present study, PPI network showed that TOP2A directly interacts with …

… To study the nature of disease mechanisms systematically, we propose a new data analysis
method to define the network biomarkers based on horizontal comparison (DNB-HC). DNB-…

… This paper proposed a pathway biomarker discovery method based on dynamic network
entropy analysis (DNEA). By employing information-theoretic entropy as a tool, using time-…