Amiodarone-induced reversible and irreversible hepatotoxicity: two case reports

T Tsuda, H Tada, Y Tanaka, N Nishida… - Journal of medical case …, 2018 - Springer
… We report the clinical and histological features of two contrasting Japanese patients with …
Histological features of amiodarone-induced hepatotoxicity are similar to alcoholic hepatitis and …

[HTML][HTML] The protective effect of grape seed and Ginkgo biloba against hepatotoxicity induced by the antidysrhythmic drug “amiodarone” in male albino rats

M Abdul-Hamid, SR Galaly, H Mahmoud… - Beni-suef university …, 2018 - Elsevier
… The aim of this study was to evaluate the possible protective effect of grape seed and
Ginkgo biloba against the hepatotoxicity induced by amiodarone through histological, …

Autophagy alleviates amiodarone-induced hepatotoxicity

F Wandrer, Ž Frangež, S Liebig, K John, F Vondran… - Archives of …, 2020 - Springer
… we analyzed the mechanisms of amiodarone-mediated liver injury. We found that amiodarone-…
-18 compared to healthy individuals or patients not receiving amiodarone. Furthermore, …

Acute hepatotoxicity of intravenous amiodarone: case report and review of the literature

CC Chen, CC Wu - American journal of therapeutics, 2016 - journals.lww.com
… The liver histology in E-ferol syndrome shows … liver toxicity due to intravenous amiodarone.
This suggests that the hepatic insult may be due to the polysorbate rather than amiodarone. …

[PDF][PDF] Hepatoprotective effect of Crocus sativus on amiodarone-induced liver toxicity

H Riaz, N Saleem, M Ahmad, Y Mehmood… - Br. J. Pharm …, 2016 - researchgate.net
Histopathological observation showed that the normal architecture … with the amiodarone
administration and histopathological slides of … Histopathologic examination of liver confirmed the …

Establishment of a mouse model for amiodarone‐induced liver injury and analyses of its hepatotoxic mechanism

S Takai, S Oda, K Tsuneyama, T Fukami… - Journal of Applied …, 2016 - Wiley Online Library
… In the analyses of liver histology, microvesicular steatosis was observed after DEX alone- or
DEX plus AMD-treated mice. No histopathological differences were observed among vehicle…

The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats

G Ibrahim Fouad, M R. Mousa - Molecular and Cellular Biochemistry, 2021 - Springer
… the histological and immunohistochemical analysis of lung … sections showed the normal
histological structure of negative … -induced hepatotoxicity, although no clear histopathological

[HTML][HTML] Hepatic dysfunction in patients receiving intravenous amiodarone

A Hashmi, NR Keswani, S Kim… - Southern medical …, 2016 - ncbi.nlm.nih.gov
… of liver toxicity among patients receiving IV amiodarone during a … Liver histology shows
Kupffer cell exfoliation, centrilobular … These histologic features are similar to the liver injury …

[HTML][HTML] Amiodarone Induced Concurrent Severe Hepatic and Pulmonary Injuries–A Case Report

HY Chang, YL Chang, CS Hung - Acta Cardiologica Sinica, 2022 - ncbi.nlm.nih.gov
… (B) High-power view of amiodarone hepatotoxicity showing ballooned cell change with
cytoplasmic … of concurrent amiodarone induced liver and lung toxicity with histopathologic proof. …

Appraisal of amiodarone-loaded PLGA nanoparticles for prospective safety and toxicity in a rat model

A Motawea, DAM Ahmed, AS Eladl, AAER El-Mansy… - Life Sciences, 2021 - Elsevier
… Besides, histopathological changes in liver and lung were … Amiodarone (AM) is a potent
antiarrhythmic drug used to treat … AM-induced hepatotoxicity can be attributed to mitochondrial …