Interferon Alpha Subtype-Specific Suppression of HIV-1 Infection In Vivo
… of the IFN-α subtype that has the most potent anti-HIV-1 activity in vivo. These studies are
now necessary to assess the complex immunomodulatory effects of different IFN-α subtypes …
now necessary to assess the complex immunomodulatory effects of different IFN-α subtypes …
The envelope gene of transmitted HIV-1 resists a late interferon gamma-induced block
… our observations using HIV-1 NL4-3, the late IFN-γ-induced block to HIV-1 NHG replication
appeared to occur posttranscriptionally in MT4 cells as IFN-γ treatment inhibited transcription …
appeared to occur posttranscriptionally in MT4 cells as IFN-γ treatment inhibited transcription …
Increased expression of IL-32 correlates with IFN-γ, Th1 and Tc1 in virologically suppressed HIV-1-infected patients
… that IL-32′s action on IFN-γ and IFN-γ secreting T cell subsets may help sustain the … HIV-1
achieving viral suppression. To explore this hypothesis, transcript levels of IL-32 and IFN-γ …
achieving viral suppression. To explore this hypothesis, transcript levels of IL-32 and IFN-γ …
Type I interferon responses by HIV-1 infection: association with disease progression and control
…, Y Konno, K Yamamoto, Y Koyanagi… - Frontiers in …, 2018 - frontiersin.org
… -I responses triggered by HIV-1 infection are detrimental for … of infection, the role of IFN-Is
produced by HIV or SIV infection in … and minuses of HIV-1 infection stimulated IFN-I responses …
produced by HIV or SIV infection in … and minuses of HIV-1 infection stimulated IFN-I responses …
The effect of antiretroviral therapy on IL-6, IL-1β, TNF-α, IFN-γ levels and their relationship with HIV-RNA and CD4+ T cells in HIV patients
… IFN-γ levels were found to be high in asymptomatic carriers and patients receiving ART [5].
Unlike other cytokines, the course of IFN-γ levels in HIV… -α, and IFN-γ in HIV-infected patients …
Unlike other cytokines, the course of IFN-γ levels in HIV… -α, and IFN-γ in HIV-infected patients …
[PDF][PDF] … of Interferon-Gamma (Ifn-γ) in Immune Response Regulation in Hiv-1 and Hiv-1+ Mycobacterium Tuberculosis (Tb) Infected Patients/Interferona-gamma (Ifn-γ) …
I Januškevica, B Rozentāle, E Hagina… - Proceedings of the …, 2016 - sciendo.com
… : 1) the serum IFN-γ level was significantly higher in the HIV-1 patient group with primary TB,
2) patients with primary HIV-1/TB had higher IFN-γ levels and HIV-1 … higher in HIV-1 patients …
2) patients with primary HIV-1/TB had higher IFN-γ levels and HIV-1 … higher in HIV-1 patients …
Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitness
…, CY Bahari, CM Shaw, Y Li… - Proceedings of the …, 2017 - National Acad Sciences
… ), and bioactive IFN levels are highly elevated during acute HIV-1 infection (37), we hypothesized
that IFN-mediated antiviral activity contributes to the HIV-1 transmission bottleneck. To …
that IFN-mediated antiviral activity contributes to the HIV-1 transmission bottleneck. To …
A computational model of inhibition of HIV-1 by interferon-alpha
… 1 interferons such as interferon-alpha (IFNα) inhibit replication of Human immunodeficiency
virus (HIV-1… impacts spreading HIV-1 infection, we modeled the interaction of HIV-1 with CD4 …
virus (HIV-1… impacts spreading HIV-1 infection, we modeled the interaction of HIV-1 with CD4 …
[HTML][HTML] Impairment of the type I interferon response by HIV-1: potential targets for HIV eradication
TS Sandstrom, N Ranganath, JB Angel - Cytokine & Growth Factor Reviews, 2017 - Elsevier
… type I IFN response in primary cell models of HIV-1 infection. … (HIV-1) can circumvent host
antiviral signalling and establish persistent viral reservoirs. HIV-1-mediated defects in the IFN …
antiviral signalling and establish persistent viral reservoirs. HIV-1-mediated defects in the IFN …
Immune activation in the course of HIV‐1 infection: causes, phenotypes and persistence under therapy
M Younas, C Psomas, J Reynes, P Corbeau - HIV medicine, 2016 - Wiley Online Library
… The surviving NKT cells during HIV-1 infection have cell surface markers of exhaustion 75,
an impaired capacity to proliferate 75 and to produce interferon γ (IFN−γ), as well as TNF-α …
an impaired capacity to proliferate 75 and to produce interferon γ (IFN−γ), as well as TNF-α …
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