New insights into the role of insulin and hypothalamic-pituitary-adrenal (HPA) Axis in the metabolic syndrome
JA Janssen - International journal of molecular sciences, 2022 - mdpi.com
… of the HPA axis plays an important etiological role in the development of the metabolic syndrome
and its … in preventing increased activation of the HPA axis and the metabolic syndrome. …
and its … in preventing increased activation of the HPA axis and the metabolic syndrome. …
Neuroendocrinological and epigenetic mechanisms subserving autonomic imbalance and HPA dysfunction in the metabolic syndrome
… These lead to defects in the hypothalamic-pituitary-adrenal axis (HPA), which may progress
… Such associations between sympathetic hyperexcitability, HPA axis hyperactivation, and …
… Such associations between sympathetic hyperexcitability, HPA axis hyperactivation, and …
HPA axis dysregulation, NR3C1 polymorphisms and glucocorticoid receptor isoforms imbalance in metabolic syndrome
… sensitivity to GC feedback, confirming the HPA axis impairment in this condition. Our data
support the emerging concept that HPA axis disruption might be involved in the incompletely …
support the emerging concept that HPA axis disruption might be involved in the incompletely …
Recent advances in the role of cortisol and metabolic syndrome in age-related degenerative diseases
A Martocchia, M Stefanelli, GM Falaschi… - Aging clinical and …, 2016 - Springer
… The hippocampus exercises an important inhibitory control over the HPA axis (mediated by
γ-aminobutyric acid, GABA) and damage to this structure may stimulate the HPA axis itself [24…
γ-aminobutyric acid, GABA) and damage to this structure may stimulate the HPA axis itself [24…
Links between HPA axis and adipokines: clinical implications in paradigms of stress-related disorders
P Papargyri, E Zapanti, N Salakos… - … & Metabolism, 2018 - Taylor & Francis
… Low adiponectin concentrations have been associated with clinical components of the
metabolic syndrome including negative association with insulin resistance [Citation103], T2DM […
metabolic syndrome including negative association with insulin resistance [Citation103], T2DM […
Hypothalamic-pituitary-adrenal (HPA) axis functioning in overtraining syndrome: findings from endocrine and metabolic responses on overtraining syndrome (EROS) …
FA Cadegiani, CE Kater - Sports Medicine-Open, 2017 - Springer
… not necessarily indicate impaired HPA axis function, but … and cardiovascular systems
to the HPA axis, rather than a … a complete evaluation of the HPA axis at different levels by …
to the HPA axis, rather than a … a complete evaluation of the HPA axis at different levels by …
[HTML][HTML] Functional hypercortisolism, visceral obesity and metabolic syndrome
L Min - Endocrine practice: official journal of the American …, 2016 - ncbi.nlm.nih.gov
… On one hand, the underweight state as occurs in patients with anorexia nervosa may
activate the HPA axis to increase adrenal cortisol production. The elevated cortisol level in the …
activate the HPA axis to increase adrenal cortisol production. The elevated cortisol level in the …
Hypothalamus-pituitary-adrenal Axis in Glucolipid metabolic disorders
Y Lin, Z Zhang, S Wang, J Cai, J Guo - … in Endocrine and Metabolic …, 2020 - Springer
… This review focuses on the role of HPA axis in GLMD and reviews the research … metabolic
syndrome [24]. FFAs are known to modulate the function of pituitary, implies that the HPA axis …
syndrome [24]. FFAs are known to modulate the function of pituitary, implies that the HPA axis …
Hair cortisol levels in posttraumatic stress disorder and metabolic syndrome
… The hypothalamic–pituitary–adrenal (HPA) axis has therefore been a logical focus of
investigation into pathophysiological pathways involved in PTSD. Although HPA axis dysfunction …
investigation into pathophysiological pathways involved in PTSD. Although HPA axis dysfunction …
Relative hypocortisolism is associated with obesity and the metabolic syndrome in recurrent affective disorders
M Maripuu, M Wikgren, P Karling, R Adolfsson… - Journal of Affective …, 2016 - Elsevier
… Before hypocortisolism has developed, HPA axis activity and cortisol levels can be expected
to fluctuate between normal and high, depending on the current state of the stress exposure…
to fluctuate between normal and high, depending on the current state of the stress exposure…
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