[HTML][HTML] Defining driver DNA methylation changes in human cancer

GP Pfeifer - International journal of molecular sciences, 2018 - mdpi.com
methylation has been deposited erroneously into such sequences by DNMT enzymes. In
many, if not all types of human cancer, these methylation … In most cancers, several hundred …

DNA methylation aberrancies as a guide for surveillance and treatment of human cancers

G Liang, DJ Weisenberger - Epigenetics, 2017 - Taylor & Francis
… of DNA methylation inhibition. This review focuses on DNA methylation changes in human
cancers, their use as biomarkers of surveillance, attributes of DNA methylation inhibition, and …

Mutual regulation of microRNAs and DNA methylation in human cancers

S Wang, W Wu, FX Claret - Epigenetics, 2017 - Taylor & Francis
… dysregulation of miRs and DNA methylation in human cancers, and highlight … and DNA
methylation. Finally, we will discuss the potential application of both miRs and DNA methylation

[HTML][HTML] A DNA methylation map of human cancer at single base-pair resolution

E Vidal, S Sayols, S Moran, A Guillaumet-Adkins… - Oncogene, 2017 - nature.com
… the DNA methylation landscape is an informative genomic feature that facilitates the
interpretation of the genetic code and the identification of functional alterations in human cancers. …

A suite of DNA methylation markers that can detect most common human cancers

L Vrba, BW Futscher - Epigenetics, 2018 - Taylor & Francis
… TCGA and GEO DNA methylation data to discover sets of DNA methylation marker regions
… and monitoring of most cancers. There are a few DNA methylation cancer markers in clinical …

[HTML][HTML] Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer

H Heyn, E Vidal, HJ Ferreira, M Vizoso, S Sayols… - Genome biology, 2016 - Springer
… a type of far-reaching DNA methylation alteration in cancer cells of the distal regulatory …
Human tumors undergo a shift in super-enhancer DNA methylation profiles that is associated …

Methods for genome-wide DNA methylation analysis in human cancer

S Fan, W Chi - Briefings in Functional Genomics, 2016 - academic.oup.com
DNA methylation has been recognized as one of the most important molecular … of human
cancers in recent years. And better understanding of the role of DNA methylation in cancer has …

DNA methylation alterations in human cancers

S Wang, W Wu - Epigenetics in Human Disease, 2018 - Elsevier
methylation level. Then, we summarized the mechanisms by which DNA methylation functions
in human cancers. … of DNA methylation in the initiation, development, and metastasis of …

[HTML][HTML] Technical advances in global DNA methylation analysis in human cancers

B Chowdhury, IH Cho, J Irudayaraj - Journal of biological engineering, 2017 - Springer
… global analysis of DNA methylation derivatives in human cancers. While, LC-MS/MS is
considered as the gold standard method for quantitative analysis of DNA methylation derivatives, …

Comparison of genome‐wide analysis techniques to DNA methylation analysis in human cancer

N Soozangar, MR Sadeghi, F Jeddi… - Journal of cellular …, 2018 - Wiley Online Library
DNA methylation was the first epigenetic modification to be detected in human cancers
with specific relation to aberrant gene expression. Herein, DNA methylation analysis explains …