A DNA methylation atlas of normal human cell types

N Loyfer, J Magenheim, A Peretz, G Cann, J Bredno… - Nature, 2023 - nature.com
… as clinical diagnosis based on circulating cell-free DNA methylation. Methylation atlas of
human cell types To portray genome-wide DNA methylation across a variety of cell types, we …

Simultaneous profiling of 3D genome structure and DNA methylation in single human cells

DS Lee, C Luo, J Zhou, S Chandran, A Rivkin… - Nature …, 2019 - nature.com
DNA methylation information and robustly separate heterogeneous cell types. Applying this
method to >4,200 single human brain prefrontal cortex cells… and differential DNA methylation, …

[HTML][HTML] DNA methylation in human diseases

Z Jin, Y Liu - Genes & diseases, 2018 - Elsevier
… of DNA methylation in common human diseases has recently been revealed. In the subsequent
sections, we discuss some recent findings on DNA methylation in these common human

Targeted DNA methylation in human cells using engineered dCas9-methyltransferases

T Xiong, GE Meister, RE Workman, NC Kato… - Scientific reports, 2017 - nature.com
… RNA-programmed targeting of methylation in human cells … to test targeted DNA methylation
in human cells. We codon-optimized the genes for expression in human cells and added …

Defining driver DNA methylation changes in human cancer

GP Pfeifer - International journal of molecular sciences, 2018 - mdpi.com
Human malignant tumors are characterized by pervasive changes in the patterns of DNA
methylation. These … It has been challenging to link specific DNA methylation changes with …

Cell division drives DNA methylation loss in late-replicating domains in primary human cells

JL Endicott, PA Nolte, H Shen, PW Laird - Nature Communications, 2022 - nature.com
… some methylation loss may occur during unscheduled, oxidative damage repair-associated
DNA … of human cells, which we call “RepliTali” (Replication Times Accumulated in Lifetime). …

The effects of DNA methylation on human psychology

F Kader, M Ghai, L Maharaj - Behavioural brain research, 2018 - Elsevier
… and lifestyle affect DNA methylation which consequently … psychological factors also modify
DNA methylation patterns. This … that DNA methylation is involved in deviant human behaviour…

Interactions between core histone marks and DNA methyltransferases predict DNA methylation patterns observed in human cells and tissues

K Fu, G Bonora, M Pellegrini - Epigenetics, 2020 - Taylor & Francis
DNA methylation, we used datasets from the Roadmap Epigenomics Project of 35 human
cells … This enabled us to perform an extensive analysis in a wide variety of human cells. We …

DNA methylation homeostasis in human and mouse development

M Iurlaro, F von Meyenn, W Reik - Current opinion in genetics & …, 2017 - Elsevier
DNA methylation as an epigenetic memory mark. However, in dividing cells, DNA methylation
… mark even if constant levels of genomic methylation are maintained over long time spans. …

The Effect of Citalopram on Genome‐Wide DNA Methylation of Human Cells

RR Kanherkar, B Getachew… - … journal of genomics, 2018 - Wiley Online Library
… as DNADNA methylation in human cells, we chose a commonly used antidepressant,
citalopram, and analyzed its effects on human cells by performing genome-wide DNA methylation