Estrogen receptor β as a prognostic marker of tumor progression in colorectal cancer with familial adenomatous polyposis and sporadic polyps

PR Stevanato Filho, S Aguiar Junior… - Pathology & Oncology …, 2018 - Springer
… We studied 120 AC Camargo Cancer Center patients diagnosed with either FAP-associated …
levels of estrogen receptor (ER)-α, ER-β and the progesterone and androgen receptors (…

Mechanisms for estrogen receptor expression in human cancer

H Hua, H Zhang, Q Kong, Y Jiang - Experimental hematology & oncology, 2018 - Springer
… The unliganded ER has been shown to be present in a cytosolic complex with hsp90 and …
hsp90 complex, receptor dimerisation, nuclear localisation and binding to estrogen response …

Epigenetic down regulation of G protein-coupled estrogen receptor (GPER) functions as a tumor suppressor in colorectal cancer

Q Liu, Z Chen, G Jiang, Y Zhou, X Yang, H Huang… - Molecular cancer, 2017 - Springer
… Then we measured the effects of G-1 on intracellular ROS accumulation by measuring the
fluorescent intensity of DCF-DA. Our results revealed that G-1 significantly increased the ROS …

Estrone sulfate transport and steroid sulfatase activity in colorectal cancer: implications for hormone replacement therapy

LC Gilligan, A Gondal, V Tang, MT Hussain… - Frontiers in …, 2017 - frontiersin.org
… protein coupled estrogen receptor (GPER), and that stimulation of this receptor with estradiol
(E … To examine if OATP inhibition by BSP reduces E 1 S intracellular substrate availability to …

[HTML][HTML] Profiling estrogen, progesterone, and androgen receptors in colorectal cancer in relation to gender, menopausal status, clinical stage, and tumour sidedness

B Refaat, A Aslam, S Idris, AH Almalki… - Frontiers in …, 2023 - frontiersin.org
Background Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR)
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous expression …

Estrogen-related receptor alpha directly binds to p53 and cooperatively controls colon cancer growth through the regulation of mitochondrial biogenesis and function

H De Vitto, J Ryu, A Calderon-Aparicio, J Monts… - Cancer & …, 2020 - Springer
… based on its homology to estrogen receptor alpha (ERα) [19, … We also measured the levels
of intracellular ROS and the … Our findings suggest the possibility of targeting colon cancers

Estrogen receptor beta: the promising biomarker and potential target in metastases

A Božović, V Mandušić, L Todorović… - International Journal of …, 2021 - mdpi.com
… in endocrine-related cancers: breast, prostate, and thyroid, and colorectal cancers. We also
… genomic action of estrogen starts upon ligand binding to the cytosolic receptor, followed by …

[HTML][HTML] G protein-coupled estrogen receptor in colon function, immune regulation and carcinogenesis

D Jacenik, EJ Beswick, WM Krajewska… - World Journal of …, 2019 - ncbi.nlm.nih.gov
estrogen receptors, ERβ, in particular, has been suggested to act as a tumor suppressor in
colorectal cancer … increased expression of GPER in the cytoplasm of mast cells, which are …

[PDF][PDF] … : Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR) receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …

VK Pidugu, S Ramadesikan, A Kulkarni, H Makala… - 2023 - academia.edu
Estrogen receptors In non-malignant tissues, the antibodies … ) labelled the cytoplasm and
nuclei of colonic epithelia, and … oestrogen receptor β in colorectal cancer patients, colon cancer

The roles of estrogen and estrogen receptors in gastrointestinal disease

C Chen, X Gong, X Yang, X Shang… - Oncology …, 2019 - spandidos-publications.com
intracellular calcium mobilization and extracellular calcium entry into ESCC cells, and estrogen
exerted an antiproliferative effect on human … risk of developing colorectal cancer (CRC) in …