… of the cancer genome, as has been recently shown by the existence of DNA hypomethylation
blocks. Our understanding of the DNA methylation patterns in human cancer has clinical …

… the human genome in the K562 immortalized human cell line. … involved in DNA
methylation-mediated gene regulation and … inter-individual variation in DNA methylation is more …

… Similar to bulk genomic DNA, we find a similar cooperative relationship between DNA
methylation levels and CpG frequency in nucleosomal DNA (Fig. 3b). This cooperative mode of …

… Distribution of DNA methylation across sequence compartments in the human genome.
Vertical axis indicates percentage of total CpG dinucleotides in each indicated compartment; …

… to genomic imprinting and cancer, the important role of DNA methylation in common human
… recent findings on DNA methylation in these common human diseases using autoimmune …

… DNA methylation (DNAm) has a critical role in regulating gene expression. Recent …
interested in the interactive analysis of DNA methylation, gene expression, and genomic variation. …

… methylated regions of the human DNA methylome. We combined a large collection of
genome-wide DNA methylation … methods, Methylation Dependent ImmunoPrecipitation followed …

… Many of the splicing events in the human genome occur co-transcriptionally while the
precursor mRNA remains associated with the chromatin until the introns are excised [61, 62]. This …

… sites, representing just 3% of around 30 million CpG sites in the human genome 10 . In …
of DNA methylation occurring in blocks, the critical functional units of DNA methylation 11,12 . …

… in the human genome. The role of DNA methylation in differential regulation of gene
expression, imprinting (differential gene expression depending on the parent-of-origin) and …