Human neural stem cells promote proliferation of endogenous neural stem cells and enhance angiogenesis in ischemic rat brain

S Ryu, SH Lee, SU Kim, BW Yoon - Neural regeneration research, 2016 - journals.lww.com
neural stem cells and their differentiation into mature neural-like cells, and enhanced
angiogenesis. This study provides valuable insights into the effect of human neural stem cell

Human neural stem cells in patients with chronic ischaemic stroke (PISCES): a phase 1, first-in-man study

D Kalladka, J Sinden, K Pollock, C Haig, J McLean… - The Lancet, 2016 - thelancet.com
… Functional improvements after treatment with human neural stem cells (hNSCs) in animal …
hNSCs=human neural stem cells. Safety was assessed by the data safety monitoring …

Functional 3D neural mini‐tissues from printed gel‐based bioink and human neural stem cells

Q Gu, E Tomaskovic‐Crook, R Lozano… - Advanced …, 2016 - Wiley Online Library
… Direct-write printing of stem cells within biomaterials … of constructing neural tissue by printing
human neural stem cells … a porous 3D scaffold encapsulating stem cells for in situ expansion …

Human neural stem cell therapy for chronic ischemic stroke: charting progress from laboratory to patients

JD Sinden, C Hicks, P Stroemer… - Stem cells and …, 2017 - liebertpub.com
… ReNeuron's development of a human neural stem cell (hNSC) therapy for chronic disability
… This review covers the progress of CTX cell therapy from its laboratory origins to the clinic, …

Restorative effects of human neural stem cell grafts on the primate spinal cord

ES Rosenzweig, JH Brock, P Lu, H Kumamaru… - Nature medicine, 2018 - nature.com
… Here we show that axons emerging from human neural stem cells extend abundant axons
through white matter, overcoming a major limiting factor in the regeneration field. In parallel, …

Attomole quantification and global profile of RNA modifications: Epitranscriptome of human neural stem cells

M Basanta-Sanchez, S Temple, SA Ansari… - Nucleic acids …, 2016 - academic.oup.com
human pluripotent stem cell-derived, neural stem cells. A wide variety of RNA modifications
were detected at levels as low as 0.0023 pg/μl, 64.09 attomoles. These results illustrate the …

Prolonged human neural stem cell maturation supports recovery in injured rodent CNS

P Lu, S Ceto, Y Wang, L Graham, D Wu… - The Journal of …, 2017 - Am Soc Clin Investig
… In particular, the human progenitor cell population differentiated, matured, and integrated …
development of these cells in humans. This study demonstrates that neural stem cells may offer …

Neural stem cell therapy—Brief review

C Grochowski, E Radzikowska… - Clinical neurology and …, 2018 - Elsevier
Stem cell sciences are a promising tool for research purposes as well as therapy. … stem
cells appear to be very useful for human neuron studies, allowing the creation of defined neuron

Efficient and fast differentiation of human neural stem cells from human embryonic stem cells for cell therapy

X Han, L Yu, J Ren, M Wang, Z Liu, X Hu… - Stem Cells …, 2017 - Wiley Online Library
neural differentiation are necessary to produce functional human neural stem cells (hNSCs)
for cell … detailed features of hNSCs originated from hES cells are still unclear. In this study, …

3K3A–activated protein C stimulates postischemic neuronal repair by human neural stem cells in mice

Y Wang, Z Zhao, SV Rege, M Wang, G Si, Y Zhou… - Nature medicine, 2016 - nature.com
… shown to stimulate neuronal production by human neural stem and progenitor cells (NSCs) …
treatment as a strategy for structural repair in the human central nervous (CNS) system. Here …