… Human serum albumin (HSA) is a globular and monomeric protein in plasma that transport
… We investigated the binding interactions of the Erlotinib Hydrochloride (Erlo) with HSA. Erlo …

… Human serum albumin (HSA) is the most abundant plasma protein with a concentration
of ∼630 μM [10]. This protein serves as a transport vehicle for a wide variety of endogenous …

… Typically, BSA was dissolved in distilled water to achieve a 5% (w/v) solution and the pH was
adjusted to 5.0 with HCl. The organic solvent was then added … Structure of serum albumin …

… was obtained by immunizing mice with an antigen conjugated with bovine serum albumin and
3… Erlotinib hydrochloride and O-desmethyl erlotinib were obtained from AdooQ BioScience …

… Erlotinib hydrochloride salt has an equilibrium solubility of approximately 0.4 mg/mL at a pH
of approximately 2 [2,7]. Erlotinib hydrochloride is … of erlotinib and gefitinib in human plasma …

… Therefore, we aim to study BSA interaction with erlotinib as an … Concentration of albumin in
human blood is approximately … bovine serum albumin (BSA) is very similar to human serum …

… erlotinib, and study its anti-cancer activity. In order to conjugate protein to ETN-4, we chosen
bovine serum albumin (… active ester 30 by first EDC·HCl coupling reaction of 29 with HOBt in …

… The BSA is structurally homologous and presents a 75.6% sequence similarity to human
serum albumin (HSA). Therefore, BSA was chosen in the present study as a substituent to HSA …

… The two most common serum albumin used as model transport proteins are BSA and
HSA (human serum albumin). There is almost 75.6% sequence homology and similar ligand …

… for their modified Erlotinib HCL formulation in comparison with free drug suspension [73].
Similarly, hyaluronic acid/human serum albumin co-modified Erlotinib HCL nanoparticles are …