Hypertonic saline versus isotonic saline nasal irrigation: systematic review and meta-analysis

D Kanjanawasee, K Seresirikachorn… - American journal of …, 2018 - journals.sagepub.com
Large volume and high-pressure saline irrigation causes better paranasal sinus penetration…
in HS over IS when studies used large volume and high-pressure devices. These effects …

Hypertonic saline in people with cystic fibrosis: review of comparative studies and clinical practice

V Terlizzi, E Masi, M Francalanci, G Taccetti… - Italian Journal of …, 2021 - Springer
… This review summarizes the current knowledge on hypertonic saline in the treatment of CF
lung disease. Furthermore, we report the real-world prescription of inhaled mucolytic agents …

Bolus therapy with 3% hypertonic saline or 0.9% saline in emergency department patients with suspected sepsis: a pilot randomised controlled trial

L Smart, SPJ Macdonald, E Bosio, D Fatovich… - Journal of critical …, 2019 - Elsevier
… We also hypothesised that hypertonic saline would reduce the volume of fluids … Lack of
treatment effect in this study may also be due to the timing of hypertonic saline delivery in relation …

Hypertonic saline in critical illness-a systematic review

CA Pfortmueller, JC Schefold - Journal of critical care, 2017 - Elsevier
Hypertonic saline induced changes … hypertonic saline results in less perioperative
complications, ICU days and mortality in selected patients. In conclusion, the use of hypertonic saline

Real world use of hypertonic saline in refractory acute decompensated heart failure: a US center's experience

M Griffin, A Soufer, E Goljo, M Colna, VS Rao, S Jeon… - Heart Failure, 2020 - jacc.org
… The purpose of this study was to investigate real world safety and efficacy of hypertonic
saline therapy in cases of refractory acute decompensated heart failure (ADHF) at a large US …

Safety of peripheral line administration of 3% hypertonic saline and mannitol in the emergency department

E Mesghali, S Fitter, K Bahjri, K Moussavi - The Journal of Emergency …, 2019 - Elsevier
Hypertonic saline (HTS) and mannitol are frequently utilized in the emergency department
(… to measured or unmeasured confounders rather than treatment with HTS or mannitol. These …

Hypertonic saline use in neurocritical care for treating cerebral edema: A review of optimal formulation, dosing, safety, administration and storage

DN Holden, JJ Mucksavage, JA Cokley… - American Journal of …, 2023 - academic.oup.com
… Current Neurocritical Care Society guidelines on the management of cerebral edema
recommend hypertonic saline (HTS) over mannitol in some scenarios, but practical questions …

Simultaneous use of hypertonic saline and IV furosemide for fluid overload: A systematic review and meta-analysis

C Liu, Z Peng, X Gao, O Gajic, Y Dong… - Critical care …, 2021 - journals.lww.com
… , BUN < 60 mg/dL, and urinary volume < 500 mL/24 hr. HSS+Fx 132 (59.85) HSS 60.62 NA
IV 1 hr infusion of 100 mL of compound hypertonic saline solution (2.8% NaCl with 0.2% KCl …

Hypertonic saline treatment in traumatic brain injury: a systematic review

M Mekonnen, V Ong, TJ Florence, K Mozaffari… - World Neurosurgery, 2022 - Elsevier
Hypertonic saline (HTS) is a widely used adjunct in the treatment of traumatic brain injury
(TBI). However, there is significant variability in practice patterns. Toward the goal of optimality …

Method of hypertonic saline administration: effects on osmolality in traumatic brain injury patients

KL Maguigan, BM Dennis, SE Hamblin… - Journal of Clinical …, 2017 - Elsevier
… Because the continuous HTS cohort received a significantly higher volume of HTS and thus
a higher chloride load, this could explain why there was a higher incidence of acute kidney …