… of STAT3 AD-HIES (eg, impaired skin and lung immunity) was … cells require the combined
activity of cytokines from STAT3-dependent, IL-17-producing CD4 + T lymphocytes (Th17 cells) …

… T-cell effector functions such as CD8 + T-cell, γδ T-cell generations … activities of TAMs correlate
with over-activated STAT3 … of TAMs STAT3 activity can enhance rat immune response to …

… -dependent feedforward signalling loops further fuel tumour progression by collectively
antagonizing the recruitment of immune effectors into the tumour bed and impairing …

… obesity negatively impacts antitumor immune responses remains largely … STAT3 in CD8 +
T effector cells is critical for obesity-associated breast tumor progression. Ablating T cell Stat3 …

… and TGF-β secreted by Treg cells can inhibit the function of CD8 + effector T-cells based on
… the activity of NADPH oxidase (NOX2), while STAT3 transcriptionally controls the activity of …

… With the potential to disrupt the tolerogenic effects of human tumors, CpG-STAT3 inhibitors
… restore the activity of cytotoxic effector cells. The combination of myeloid cell-specific STAT3 …

… of STAT3. The overexpression of PIAS3, a negative regulator of STAT3 activity leads to
decreased STAT3 … to and methylates STAT3, leading to enhanced STAT3 activity by increased …

… proteins associated to STAT1, STAT3, and in certain cases … cells has been observed to
promote the JAK1-TYK2-STAT3 … functional activity of effector cells and antigen-presenting cells…

… Infiltration of CD3 + T cells and Granzyme B + effector cells was significantly increased in
MT/Shc 2F/2F tumours (P<0.0001 by Mann–Whitney U-test) (Fig. 1e and Supplementary Fig. 2a…

… Cytokines can also modulate the effector functions of immune cells in a STAT3-dependent …
STAT3 activity promotes an oncogenic transcription profile in tumor cells that supports cell …