Cancer immunotherapy by blocking immune checkpoints on innate lymphocytes
… successful cancer immunotherapy strategies … innate lymphocytes by ICI in both solid tumors
and hematological malignancies. Overall, we believe that, in our near future, immunotherapy …
and hematological malignancies. Overall, we believe that, in our near future, immunotherapy …
Immune checkpoints and innate lymphoid cells—new avenues for cancer immunotherapy
N Jacquelot, M Ghaedi, K Warner, DC Chung… - Cancers, 2021 - mdpi.com
… opportunities in cancer. Ideally innate lymphocyte responses would be modulated to work
in parallel with anti-tumor T cells to promote potent and long-lasting anti-tumor immunity. …
in parallel with anti-tumor T cells to promote potent and long-lasting anti-tumor immunity. …
Exploring innate immunity in cancer immunotherapy: opportunities and challenges
… -based immunotherapies. Notably, myeloid cells and innate lymphocytes contribute to both
… Finally, selective context-specific targeting of the innate immune system has the potential to …
… Finally, selective context-specific targeting of the innate immune system has the potential to …
Innate immune signaling and regulation in cancer immunotherapy
L Corrales, V Matson, B Flood, S Spranger… - Cell research, 2017 - nature.com
… cancer immunotherapies. The generation of a spontaneous T cell response against tumor-associated
antigens depends on innate … , suggesting that failed innate immune activation may …
antigens depends on innate … , suggesting that failed innate immune activation may …
Targeting innate immune pathways for cancer immunotherapy
LL Cao, JC Kagan - Immunity, 2023 - cell.com
… The innate immune system is critical for inducing durable and protective T cell responses to
… for cancer immunotherapy. In this review, we present a framework wherein distinct innate …
… for cancer immunotherapy. In this review, we present a framework wherein distinct innate …
[HTML][HTML] Helper-like innate lymphoid cells and cancer immunotherapy
A Crinier, E Vivier, M Blery - Seminars in Immunology, 2019 - Elsevier
… the emergence of cancer immunotherapy, a new kind of therapeutic strategy in which the
immune system is boosted, to enable it to kill tumor cells [5]. Immunotherapies may target the …
immune system is boosted, to enable it to kill tumor cells [5]. Immunotherapies may target the …
[HTML][HTML] The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy
… A critical concept underlying the current view of immunotherapy is that the ultimate end-effector
and therapeutic target of cancer immunotherapy is the tumour-specific T-cell. An …
and therapeutic target of cancer immunotherapy is the tumour-specific T-cell. An …
Harnessing innate immunity in cancer therapy
… to enhance the efficacy of both endogenous protective antitumour antibodies involved in
immunosurveillance and exogenous antitumour antibodies used in cancer immunotherapy. …
immunosurveillance and exogenous antitumour antibodies used in cancer immunotherapy. …
Promising targets for cancer immunotherapy: TLRs, RLRs, and STING-mediated innate immune pathways
K Li, S Qu, X Chen, Q Wu, M Shi - International journal of molecular …, 2017 - mdpi.com
… synergistic effects in cancer immunotherapy have been evidenced when innate and adaptive
… innate and adaptive immune responses is necessary for efficient cancer immunotherapy. …
… innate and adaptive immune responses is necessary for efficient cancer immunotherapy. …
Innate lymphoid cells and cancer
… Despite the unprecedented success of this first wave of cancer immunotherapies based
on immune checkpoint inhibitors and CAR T cells, many people fail to benefit from such …
on immune checkpoint inhibitors and CAR T cells, many people fail to benefit from such …
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