Intranasal oxytocin alleviates comorbid depressive symptoms in neuropathic pain via elevating hippocampal BDNF production in both female and male mice
R Liu, D Sun, X Xing, Q Chen, B Lu, B Meng, H Yuan… - …, 2024 - Elsevier
… Because of the advantage of intranasal delivery of oxytocin … effect of intranasal application
of oxytocin on neuropathic pain and … the effect of intranasal oxytocin on neuropathic pain and …
of oxytocin on neuropathic pain and … the effect of intranasal oxytocin on neuropathic pain and …
Intranasal oxytocin attenuates reactive and ongoing, chronic pain in a model of mild traumatic brain injury
AC Meidahl, A Eisenried, M Klukinov… - … Head and Face Pain, 2018 - Wiley Online Library
… is characterized by allodynia and resembles that found in other central neuropathic pain
patients.6 Headache is also a common post-TBI manifestation in humans and the symptoms …
patients.6 Headache is also a common post-TBI manifestation in humans and the symptoms …
Intranasal administration for pain: oxytocin and other polypeptides
… pain, but not in men [61]. Similarly, a recent study on the perception of wound pain showed
that intranasal oxytocin reduced wound pain in … nerve—and have shown that nasal oxytocin …
that intranasal oxytocin reduced wound pain in … nerve—and have shown that nasal oxytocin …
Evaluating the efficacy of intranasal oxytocin on pain and function among individuals who experience chronic pain: a protocol for a multisite, placebo-controlled …
JA Rash, TS Campbell, L Cooper, D Flusk… - BMJ open, 2021 - bmjopen.bmj.com
… with primary neuropathic pain—pain arising as a direct consequence of a lesion or disease
affecting the central or peripheral nervous system46—will be eligible. Neuropathic pain will …
affecting the central or peripheral nervous system46—will be eligible. Neuropathic pain will …
Ventrolateral orbital cortex oxytocin attenuates neuropathic pain through periaqueductal gray opioid receptor
M Taati, E Tamaddonfard - Pharmacological Reports, 2018 - Elsevier
… Oxytocin plays an important role in supraspinal modulation of pain. In the present study, we
… (VLOC) microinjection of oxytocin on neuropathic pain after blockade of opioid receptors in …
… (VLOC) microinjection of oxytocin on neuropathic pain after blockade of opioid receptors in …
Oxytocin and pain perception: from animal models to human research
S Boll, ACA De Minas, A Raftogianni, SC Herpertz… - Neuroscience, 2018 - Elsevier
… of pain perception only. The intranasal administration of OT did not reduce ischemic pain
sensitivity, but resulted in enhanced pain inhibition on the masseter, but not the forearm in a …
sensitivity, but resulted in enhanced pain inhibition on the masseter, but not the forearm in a …
Preliminary results from a randomized, controlled, cross-over trial of intrathecal oxytocin for neuropathic pain
JC Eisenach, RS Curry, TT Houle - Pain Medicine, 2023 - academic.oup.com
… administration at dose orders of magnitude greater than are tested in humans, and human
studies, which typically utilize intranasal oxytocin administration, are as likely to show no …
studies, which typically utilize intranasal oxytocin administration, are as likely to show no …
Up‐regulation of oxytocin receptors on peripheral sensory neurons mediates analgesia in chemotherapy‐induced neuropathic pain
L Li, P Li, J Guo, Y Wu, Q Zeng, N Li… - British Journal of …, 2023 - Wiley Online Library
… The activation of oxytocin receptor (OXTR) mediated the antinociceptive effects of
intravenous injection of oxytocin (OXT) on paclitaxel (PTX)-induced neuropathic pain. (a) The …
intravenous injection of oxytocin (OXT) on paclitaxel (PTX)-induced neuropathic pain. (a) The …
Nasal oxytocin for the treatment of psychiatric disorders and pain: achieving meaningful brain concentrations
DC Yeomans, LR Hanson, DS Carson… - Translational …, 2021 - nature.com
… concentrations of oxytocin observed along the trigeminal nerve and pons, medulla, and
cerebellum in the present study appear to also suggest a route along the trigeminal nerve that …
cerebellum in the present study appear to also suggest a route along the trigeminal nerve that …
Intranasal oxytocin as a treatment for chronic pelvic pain: A randomized controlled feasibility study
… , interstitial cystitis, functional bowel disorder, fibromyalgia, neuropathic pain, or lower
abdominal pain with no evidence of pelvic floor myalgia; and/or (8) only experienced …
abdominal pain with no evidence of pelvic floor myalgia; and/or (8) only experienced …
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