[HTML][HTML] Cellular and molecular pathways of renal repair after acute kidney injury

S Kumar - Kidney International, 2018 - Elsevier
… In conclusion, much progress has been made in identifying the cell type that drives the
nephron epithelial repair responses after injury and during epithelial homeostasis. …

Cellular plasticity in kidney injury and repair

M Chang-Panesso, BD Humphreys - Nature Reviews Nephrology, 2017 - nature.com
… to our understanding of repair after kidney injury, including epithelial regeneration. Here we
… cellular hierarchies and mechanisms underlying kidney injury and repair, with a particular …

Epithelial cell states associated with kidney and allograft injury

C Hinze, S Lovric, PF Halloran, J Barasch… - Nature Reviews …, 2024 - nature.com
… cells from kidney or urine have identified a role for kidney injury-induced epithelial cell states
… normal kidney epithelium through a process of adaptive repair, a subset of dedifferentiated …

Kidney injury molecule-1 (KIM-1) mediates renal epithelial cell repair via ERK MAPK signaling pathway

Z Zhang, CX Cai - Molecular and cellular biochemistry, 2016 - Springer
… and regenerating renal proximal tubular epithelial cells following … repair process. In the
present study, we report that expression of KIM-1 facilitates renal tubular epithelial cell repair by …

[HTML][HTML] Autophagy, innate immunity and tissue repair in acute kidney injury

P Duann, EA Lianos, J Ma, PH Lin - International journal of molecular …, 2016 - mdpi.com
epithelium is endowed with high mitochondria density for their function in active transport.
Acute kidney injury (… AKI results in acute cell death and necrosis of renal tubule epithelial cells …

[HTML][HTML] Wnt/β-catenin signaling in kidney injury and repair: a double-edged sword

D Zhou, RJ Tan, H Fu, Y Liu - Laboratory investigation, 2016 - Elsevier
… 64 Kidney injury repair following AKI involves several distinct biologic events including
tubular damage/cell death, epithelial–mesenchymal communication (EMC), tubular cell …

Epithelial proliferation and cell cycle dysregulation in kidney injury and disease

K Lee, GL Gusella, JC He - Kidney international, 2021 - Elsevier
… of kidney injury and repair, it has long been held that a complete recovery was possible
following an acute kidney injury (AKI), … However, recent evidence indicates that the repair is often …

WNT–β-catenin signalling—a versatile player in kidney injury and repair

SJ Schunk, J Floege, D Fliser, T Speer - Nature Reviews Nephrology, 2021 - nature.com
epithelial cells; DKK3 drives kidney fibrosis and is associated with short-term risk of CKD
progression and acute kidney injury. … strategy in kidney injury and associated complications. …

[HTML][HTML] Molecular mechanisms of the acute kidney injury to chronic kidney disease transition: an updated view

F Guzzi, L Cirillo, RM Roperto, P Romagnani… - International journal of …, 2019 - mdpi.com
… Both resident and infiltrating immune cells participate in inflammation, injury and repair in
the acute phase of kidney injury; through a tight cross-talk with endothelial cells, epithelial cells…

Signaling crosstalk between tubular epithelial cells and interstitial fibroblasts after kidney injury

RJ Tan, D Zhou, Y Liu - Kidney diseases, 2016 - karger.com
… Initial responses are likely an attempt at kidney repair and recapitulate embryologic … that
these epithelial cells have excellent regenerative capacity after mild acute kidney injuries (AKI), …