[HTML][HTML] Understanding MAPK signaling pathways in apoptosis

J Yue, JM López - International journal of molecular sciences, 2020 - mdpi.com
… We also describe the basic signaling properties of MAPKs (ultrasensitivity, hysteresis, digital
response), and the presence of different positive feedback loops in apoptosis. We provide a …

Functional analysis of the MAPK pathways in fungi

D Martínez-Soto, J Ruiz-Herrera - Revista iberoamericana de micologia, 2017 - Elsevier
… expression in response to them. In all species of fungi, the MAPK pathways have important
… cell cycle control, mating, morphogenesis, response to different stresses, resistance to UV …

Spatial and temporal signal processing and decision making by MAPK pathways

O Atay, JM Skotheim - Journal of Cell Biology, 2017 - rupress.org
… As the MAPK pathway response is both fast and graded, there is no obvious mechanism
to prevent signaling fluctuations from dominating decision making. This raises the question of …

Co-occurring alterations in the RAS–MAPK pathway limit response to MET inhibitor treatment in MET exon 14 skipping mutation-positive lung cancer

JK Rotow, P Gui, W Wu, VM Raymond, RB Lanman… - Clinical Cancer …, 2020 - AACR
… Prominent co-occurring RAS–MAPK pathway gene … MET TKI treatment response and
RAS–MAPK pathway co-… or NF1 downregulation hyperactivated MAPK signaling to promote MET …

[HTML][HTML] Understanding the role of p38 and JNK mediated MAPK pathway in response to UV-A induced photoaging in Caenorhabditis elegans

MI Prasanth, S Gayathri, JP Bhaskar, V Krishnan… - … of Photochemistry and …, 2020 - Elsevier
… in eliciting a response against UV-A exposure, which was further validated by Western blot
… that MAPK pathway could play an important part in initiating and eliciting a response by the …

Response of MAPK pathway to iron oxide nanoparticles in vitro treatment promotes osteogenic differentiation of hBMSCs

Q Wang, B Chen, M Cao, J Sun, H Wu, P Zhao, J Xing… - Biomaterials, 2016 - Elsevier
… of the roles of MAPK pathway in our … MAPK pathway, we performed ALP activity assay to
detect whether the osteogenesis level could be changed by the inhibition of this pathway. For …

[HTML][HTML] ERK/MAPK signalling pathway and tumorigenesis

YJ Guo, WW Pan, SB Liu… - Experimental and …, 2020 - spandidos-publications.com
… , differentiation, apoptosis and stress responses. The MAPK pathway includes three main
kinases, MAPK kinase kinase, MAPK kinase and MAPK, which activate and phosphorylate …

[HTML][HTML] A comprehensive review on MAPK: a promising therapeutic target in cancer

C Braicu, M Buse, C Busuioc, R Drula, D Gulei… - Cancers, 2019 - mdpi.com
responses. Thus, in this review, we discuss the many implications of the MAPK pathways in
cancer, … emphasis of MAPK crosstalk with key signaling pathways in pathological conditions. …

Angiotensin II-induced early and late inflammatory responses through NOXs and MAPK pathways

X Zhang, J Yang, X Yu, S Cheng, H Gan, Y Xia - Inflammation, 2017 - Springer
response and how signal transduction through mitogen-activated protein kinase (MAPK)
pathways… -dependent reactions in response to Ang II stimulation via MAPK pathways. First, ROS …

Clinical responses and persistent BRAF V600E+ blood cells in children with LCH treated with MAPK pathway inhibition

OS Eckstein, J Visser… - Blood, The Journal …, 2019 - ashpublications.org
MAPK pathway inhibition in adults with LCH and/or ECD have demonstrated promising
response rates, the efficacy and safety of MAPK pathway … for responses to MAPK inhibition. The …