Mast cells and IgE in defense against venoms: possible “good side” of allergy?

SJ Galli, P Starkl, T Marichal, M Tsai - Allergology international, 2016 - jstage.jst.go.jp
… that mast cells can enhance innate resistance to reptile or arthropod venoms during a first
exposure to such venoms… can limit snake venom toxicity. J Allergy Clin Immunol. In press (Ref. …

IgE and mast cells in host defense against parasites and venoms

K Mukai, M Tsai, P Starkl, T Marichal… - Seminars in …, 2016 - Springer
snake venoms puts them at risk for having a potentially fatal anaphylactic reaction upon
subsequent exposure to such venoms. … responses associated with mast cell activation and IgE is …

[HTML][HTML] Mast cells and IgE can enhance survival during innate and acquired host responses to venoms

SJ Galli, P Starkl, T Marichal, M Tsai - Transactions of the American …, 2017 - ncbi.nlm.nih.gov
… local anaphylaxis can limit snake venom toxicity. J Allergy … venoms also can induce mast
cell degranulation in vitro. So, I think that it is very likely that many venoms can induce mast cell

Mast cells and IgE in defense against lethality of venoms: Possible “benefit” of allergy

SJ Galli, M Metz, P Starkl, T Marichal, M Tsai - Allergo journal international, 2020 - Springer
… of the venoms of six different poisonous snakes [84]. … venom or Russell’s viper venom,
which “arm” mast cells with IgE antibodies that bear specificity for components of those venoms, …

Human mast cell tryptase is a potential treatment for snakebite envenoming across multiple snake species

E Anderson, K Stavenhagen, D Kolarich… - Frontiers in …, 2018 - frontiersin.org
… Based on previous reports by us and others showing that mouse MC proteases are able
to detoxify snake venom or snake venom components (13, 29), we hypothesized that the …

Bothrops jararacussu snake venom lectin induces mast cell activation and vascular permeability enhance in an animal model

FH Kwasniewski, AM Kayano, AN Fukunaga… - Toxicon, 2022 - Elsevier
… jararacussu snake venom, on mast cells and vasopermeability were investigated in this
study. BjcuL activates mast cells and increases vasopermeability through the involvement of …

Snake venom rhodocytin induces plasma extravasation via toxin-mediated interactions between platelets and mast cells

Y Nakamura, T Sasaki, C Mochizuki, K Ishimaru… - Scientific Reports, 2019 - nature.com
… did not directly stimulate mast cells, and mast cells did not express CLEC-… mast cell activation
by snake venom: some toxins may activate mast cells indirectly, with platelets or other cells

[HTML][HTML] Mast cells as protectors of health

A Dudeck, M Köberle, O Goldmann, N Meyer… - Journal of Allergy and …, 2019 - Elsevier
… and elimination of toxins or venoms. MCs can enhance … Uterine tissue remodeling by α-chymase
(mast cell protease [… detoxify an increasing number of venoms and endogenous toxins. …

The mast cell-IgE paradox: from homeostasis to anaphylaxis

SJ Galli - The American journal of pathology, 2016 - Elsevier
… that mast cells can enhance innate host resistance to reptile or arthropod venoms during …
to a first exposure to the venoms of three species of poisonous snakes, the Gila monster, the …

An overview of the immune modulating effects of enzymatic toxins from snake venoms

SM Burin, DL Menaldo, SV Sampaio, FG Frantz… - International journal of …, 2018 - Elsevier
… 1 depicts the effect of snake venom PLA 2 s in mast cell activation and the consequent
release of histamine and other mediators of inflammation, such as platelet-activating factor (PAF), …