Generation of equine-induced pluripotent stem cells and analysis of their therapeutic potential for muscle injuries

EM Lee, AY Kim, EJ Lee, JK Park, SI Park… - Cell …, 2016 - journals.sagepub.com
Mesenchymal stem cells (MSCs), embryonic stem cells (… and mouse iPSCs during muscle
regeneration in preclinical … the generation of iPSCs from equine adipose-derived stem cells (E-…

Characterization of the proteins secreted by equine muscle-derived mesenchymal stem cells exposed to cartilage explants in osteoarthritis model

L Dechêne, M Colin, C Demazy, M Fransolet… - Stem cell reviews and …, 2023 - Springer
… of muscle-derived MSCs (mdMSCs) as skeletal muscle has the advantage to represent more
than 40% of horse … In this study, we explored the potential of equine mdMSCs as a potential …

The usefulness of mesenchymal stem cells beyond the musculoskeletal system in horses

A Cequier, C Sanz, C Rodellar, L Barrachina - Animals, 2021 - mdpi.com
… The main target of mesenchymal stem cell therapy in horses has long been the locomotor
… Originally, mesenchymal stem cells were thought to act by just differentiating into the cells of …

From skeletal muscle to stem cells: An innovative and minimally-invasive process for multiple species

J Ceusters, JP Lejeune, C Sandersen, A Niesten… - Scientific reports, 2017 - nature.com
… and easy-to-use technique of skeletal muscle-derived mesenchymal stem cell harvest, culture,
equine pluripotent stem cells, we basically developed our technique on equine muscles. …

Muscle derived mesenchymal stem cells inhibit the activity of the free and the neutrophil extracellular trap (NET)-bond myeloperoxidase

T Franck, J Ceusters, H Graide, A Mouithys-Mickalad… - Cells, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) are known to migrate to … effect of equine mesenchymal
stem cells derived from muscle … released by stimulated equine neutrophils. After specific …

Isolation and characterization of equine endometrial mesenchymal stromal cells

BE Rink, KR Amilon, CL Esteves, HM French… - Stem cell research & …, 2017 - Springer
… Because of the difficulty of clearly distinguishing smooth muscle cells from undifferentiated
MSCs, we assessed the expression of early (ACTA2), intermediate (CNN1), and mature (…

[HTML][HTML] Intramuscular transplantation of allogeneic mesenchymal stromal cells derived from equine umbilical cord

MC Dias, F da Cruz Landim-Alvarenga… - … of Stem Cells, 2016 - synapse.koreamed.org
… Our results showed that the application of horse UC-MSCs into muscle tissue in the conditions
performed in this experiment did not incite systemic inflammatory response. In a recent …

Optimization of the Amplification of Equine Muscle-Derived Mesenchymal Stromal Cells in a Hollow-Fiber Bioreactor

J Duysens, H Graide, A Niesten… - Methods and …, 2024 - mdpi.com
… injections of 1 to 2 million cells per kilogram of body weight … capacity of equine muscle-derived
mesenchymal stromal cells (… Quantum™ Cell Expansion System (Terumo Blood and Cell

Equine mesenchymal stem cells: properties, sources, characterization, and potential therapeutic applications

MB Gugjoo, GT Sharma - Journal of equine veterinary science, 2019 - Elsevier
… In horse, … mesenchymal stem cells [16], which may pave the way for autologous iPSCs
therapy in the future (Fig. 1). As of now in horse regenerative medicine, mesenchymal stem cells (…

Differentiation of equine induced pluripotent stem cells into mesenchymal lineage for therapeutic use

MJ Chung, SY Park, JY Son, JY Lee, HH Yun, EJ Lee… - Cell Cycle, 2019 - Taylor & Francis
… line (E-iPSCs) from equine adipose-derived stem cells (ASCs) … established E-iPSCs into
mesenchymal stem cells (MSCs) by … that can be collected easily from muscles, adipose, or other …