Systematic review with metaanalysis: efficacy and safety of oral Janus kinase inhibitors for inflammatory bowel disease

C Ma, JK Lee, AR Mitra, A Teriaky… - Alimentary …, 2019 - Wiley Online Library
… In our meta-analysis, we did not identify JAK1 selectivity as associated with efficacy or
safety in meta-regression. This may reflect loss of JAK isoform selectivity at higher doses and …

Systematic review and metaanalysis: efficacy and safety of early biologic treatment in adult and paediatric patients with Crohn's disease

RC Ungaro, S Aggarwal, O Topaloglu… - Alimentary …, 2020 - Wiley Online Library
… To our knowledge, this is the most comprehensive systematic review and meta-analysis on
outcomes of early biologic use in CD. The meta-analysis findings confirm our hypothesis that …

Efficacy and safety of varicocelectomies: A meta-analysis

R Yuan, H Zhuo, D Cao, Q Wei - Systems biology in reproductive …, 2017 - Taylor & Francis
This study reviewed the efficacy and safety of the three surgical approaches for varicocele (microsurgical,
laparoscopic, and open varicocelectomy). A systematic review of the relevant …

Efficacy and safety of mipomersen: a systematic review and meta-analysis of randomized clinical trials

F Fogacci, N Ferri, PP Toth, M Ruscica, A Corsini… - Drugs, 2019 - Springer
efficacy and safety of mipomersen through a systematic review of the literature and a
meta-analysis … bias in the current meta-analysis (p > 0.05 always). Finally, the classic fail-…

Comparative efficacy and safety of first-line antiretroviral therapy for the treatment of HIV infection: a systematic review and network meta-analysis

S Kanters, M Vitoria, M Doherty, ME Socias, N Ford… - The lancet HIV, 2016 - thelancet.com
Background New antiretroviral therapy (ART) regimens for HIV could improve clinical
outcomes for patients. To inform global guidelines, we aimed to assess the comparative …

… meta-analysis efficacy and safety of immune checkpoint inhibitors in advanced melanoma patients with anti-PD-1 progression: a systematic review and meta-analysis

NN Alrabadi, HM Abushukair, OE Ababneh… - Clinical and …, 2021 - Springer
efficacy and safety of secondary treatments for these patients are still not well established.
Here, we evaluate the efficacy and safety … to assess the efficacy and safety of different FDA-…

[HTML][HTML] Efficacy and safety of COVID-19 vaccines: a systematic review and meta-analysis of randomized clinical trials

A Pormohammad, M Zarei, S Ghorbani, M Mohammadi… - Vaccines, 2021 - mdpi.com
meta-analysis, we provide systematic and comprehensive data regarding the vaccines’ safety,
efficacy, … Here, we mainly focused on available RCTs publications on the safety, efficacy, …

The efficacy and safety of first-line chemotherapy in advanced esophagogastric cancer: a network meta-analysis

E Ter Veer, N Haj Mohammad… - Journal of the …, 2016 - academic.oup.com
Background: A globally accepted standard first-line chemotherapy regimen in advanced
esophagogastric cancer (AEGC) is not clearly established. We conducted a systematic review to …

Efficacy and safety of umifenovir for coronavirus disease 2019 (COVID‐19): A systematic review and metaanalysis

D Huang, H Yu, T Wang, H Yang… - Journal of medical …, 2021 - Wiley Online Library
meta-analysis indicates that umifenovir has good safety and tolerability but limited efficacy.
… outcome variables which we did not use in current meta-analysis. For example, it is reported …

Analgesic efficacy and safety of curcuminoids in clinical practice: a systematic review and meta-analysis of randomized controlled trials

A Sahebkar, Y Henrotin - Pain medicine, 2016 - academic.oup.com
… However, our meta-analysis is limited by the inherent potential for publication bias. … , this
meta-analysis of RCTs with low risk of bias shows that curcuminoids supplements may be a safe