miRNAs role in cervical cancer pathogenesis and targeted therapy: Signaling pathways interplay

AS Doghish, MA Ali, SS Elyan, MA Elrebehy… - … -Research and Practice, 2023 - Elsevier
Cervical cancer (CC) is the primary cause of cancer deaths in underdeveloped countries.
The persistence of infection with high-risk human papillomavirus (HPV) is a significant
contributor to the development of CC. However, few women with morphologic HPV infection
develop invasive illnesses, suggesting other mechanisms contribute to cervical
carcinogenesis. MicroRNAs (miRNAs, miRs) are small chain nucleic acids that can regulate
wide networks of cellular events. They can inhibit or degrade their target protein-encoding …
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