… The microphthalmia (MiT) subfamily of transcription factors includes TFE3, TFEB, TFEC, and
… by the rearrangement of the MiT transcription factors TFE3 and TFEB, respectively. Recent …

… [45] and called them mi/mi (for microphthalmia) mice. The gene encoding the protein whose
… a transcription factor (TF) that was called MiTF for Microphthalmia Transcription Factor. MiTF …

… TFE3 encodes a member of the microphthalmia transcription factor (MiT) basic helix-loop-helix
family of transcription factors which includes TFE3, TFEB and MITF. Recently, a variant in …

… We have shown here that mutations in a transcription factor expressed in the RPE, and not
… essential for vision, and that transcription factors whose expression in the eye is restricted to …

… microphthalmia-associated transcription factor, MITF, which plays a central role in the
development and function of RPE cells, regulates the expression … We conclude that the expression …

… pigmentation and loss of chromosome 3/loss of expression of the BAP1 gene [16]. As MITF
(microphthalmia-associated transcription factor) plays a major role in regulating pigmentation…

… transcription factors specify discrete cell types. In melanocytes, MITF (microphthalmia-associated
transcription factor) has a dominant role that has been termed ‘master transcriptional …

… We show that in addition to the expression defects in key transcription factors, Rbm24 −/−
mice exhibit reduced Birc2 and JAG1, which offers an explanation for the elevated apoptosis in …

… that are negatively regulated by this multifunctional transcription factor. In sum, our results
provide new evidence that MITF works as a transcriptional repressor to play a functional role in …

… study reveals that the microphthalmia (MiT)/transcription factor E (TFE) family members
are novel regulators of hepcidin transcription. Melanocyte-inducing transcription factor (MITF)-A, …