[HTML][HTML] The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology

A Kawakami, DE Fisher - Laboratory investigation, 2017 - Elsevier
transcription factors specify discrete cell types. In melanocytes, MITF (microphthalmia-associated
transcription factor… functions of the MITF transcription factor have revealed fundamental …

The underestimated role of the microphthalmia-associated transcription factor (MiTF) in normal and pathological haematopoiesis

A Oppezzo, F Rosselli - Cell & Bioscience, 2021 - Springer
… /mi phenotype was cloned in 1993 and found to encode a transcription factor (TF) that
was called MiTF for Microphthalmia Transcription Factor. MiTF is a member of the basic-helix-loop-…

Clinical and molecular characterization of microphthalmia-associated transcription factor (MITF)-related renal cell carcinoma

M Lang, CD Vocke, CJ Ricketts, AR Metwalli, MW Ball… - Urology, 2021 - Elsevier
… member of the microphthalmia transcription factor (MiT) basic helix-loop-helix family of
transcription factors which includes TFE3, TFEB and MITF. Recently, a variant in the MITF gene, c.…

The microphthalmia-associated transcription factor (Mitf) gene and its role in regulating eye function

A García-Llorca, SG Aspelund, MH Ogmundsdottir… - Scientific reports, 2019 - nature.com
MITF protein is a member of the MYC supergene family of basic-helix-loop-helix-leucine-zipper
(bHLHZip) transcription factors … The MITF transcription factor is composed of a basic DNA …

Microphthalmia-associated transcription factor in senescence and age-related diseases

J Zhang, Y Mou, H Gong, H Chen, H Xiao - Gerontology, 2021 - karger.com
… In summary, MITF is an active transcription factor involved in the regulation of DNA damage
and repair, which makes its interaction with DNA damage-related senescence conceivable. …

Microphthalmia-associated transcription factor (MiTF): promiscuous staining patterns in fibrohistiocytic lesions is a potential pitfall

SK Mohanty, S Sharma, D Pradhan… - … -Research and Practice, 2018 - Elsevier
Microphthalmia-associated transcription factor (MiTF) is used as a marker of melanocytic
differentiation. However, MiTF … misdiagnosed as melanoma based on MiTF immunoreactivity. …

Negative regulatory loop between microphthalmia-associated transcription factor (MITF) and notch signaling

T Golan, C Levy - International Journal of Molecular Sciences, 2019 - mdpi.com
… loop between Notch signaling and microphthalmia-associated transcription factor (MITF), the
MITF transcriptional activity, inhibits the transcription of MITF, leading to a decrease in MITF

Microphthalmia Transcription Factor almost Thirty Years after: Its Role in Melanogenesis and its Plant-Derived Inhibitors

D Firmansyah, S Indriaty, SA Sumiwi… - Research Journal of …, 2022 - indianjournals.com
… specific transcription factor for melanocytes9,10. MITF is a group of microphthalmia transcription
factors … genes, ie MITF, transcription factor EB (TFEB), transcription factor E3 (TFE3), and …

Microphthalmia-associated transcription factor: a differentiation marker in uveal melanoma

MC Gelmi, RM Verdijk, LE Houtzagers… - International Journal of …, 2023 - mdpi.com
Microphthalmia-associated transcription factor (MITF) is an … As MITF (microphthalmia-associated
transcription factor) plays a … , we became interested in the function of MITF in UM. …

Molecular and functional analysis of the microphthalmia-associated transcription factor (mitf) gene duplicates in red tilapia

B Jiang, L Wang, M Luo, W Zhu, J Fu, Z Dong - … and Physiology Part A …, 2022 - Elsevier
… , the microphthalmia-associated transcription factor (mitf) is at … After injecting mitf-dsRNA
duplicates along the tail vein of … These findings suggest that mitf gene duplicates may play an …