Identification of Streptococcus pneumoniae and other Mitis streptococci: importance of molecular methods

E Sadowy, W Hryniewicz - European Journal of Clinical Microbiology & …, 2020 - Springer
… review, including PCR- and gene sequencing-based tests as … in our understanding of
relationships within the Mitis group. … by several molecular and other approaches and the purpose …

Whole genome sequencing as a tool for phylogenetic analysis of clinical strains of Mitis group streptococci

LH Rasmussen, R Dargis, K Højholt… - European Journal of …, 2016 - Springer
… As the seven housekeeping genes were extracted from WGS in our study, the amplification
… As WGS becomes more available to the routine laboratories, multi-gene approaches for …

StreptoBase: An Oral Streptococcus mitis Group Genomic Resource and Analysis Platform

W Zheng, TK Tan, IC Paterson, NVR Mutha, CC Siow… - PloS one, 2016 - journals.plos.org
mitis group bacteria and putative virulence genes profile across multiple streptococcal strains…
their genes of interest are potential virulence genes using a sequence homology approach. …

Population genomics of Streptococcus mitis in UK and Ireland bloodstream infection and infective endocarditis cases

A Kalizang'oma, D Richard… - Nature …, 2024 - nature.com
… Here we show, using a pilot phylogenetic-based GWAS-type approach, that some genes
may be overrepresented in disease when compared to carriage isolates, which may potentially …

Resolving Phylogenetic Relationships for Streptococcus mitis and Streptococcus oralis through Core- and Pan-Genome Analyses

IM Velsko, MS Perez, VP Richards - Genome biology and …, 2019 - academic.oup.com
… Restructuring of the mitis group’s Streptococcus species used three approaches, … gene
content is not correlated with core or gene consensus phylogenies. Gene content trees of mitis

Novel Multilocus Sequence Typing and Global Sequence Clustering Schemes for Characterizing the Population Diversity of Streptococcus mitis

A Kalizang'oma, B Kwambana-Adams… - Journal of Clinical …, 2023 - Am Soc Microbiol
… To assess the utility of the genomic tools in resolving the genetic relatedness of S. mitis
isolates, our MLST and global clustering approaches were applied to carriage isolates obtained …

Relationships among streptococci from the mitis group, misidentified as Streptococcus pneumoniae

E Sadowy, A Bojarska, A Kuch, A Skoczyńska… - European Journal of …, 2020 - Springer
… The aim of our study was to investigate these isolates using a genomic approach in order
to better understand their mutual genetic relationships and position within the Mitis group, …

Overcoming the Barrier of Low Efficiency during Genetic Transformation of Streptococcus mitis

G Salvadori, R Junges, DA Morrison… - Frontiers in …, 2016 - frontiersin.org
… genome editing approaches in S. mitis functional investigations. The aim of this study was
to identify optimal conditions for natural genetic transformation in Streptococcus mitis, and to …

Improved differentiation of Streptococcus pneumoniae and other S. mitis group streptococci by MALDI Biotyper using an improved MALDI Biotyper database content …

I Harju, C Lange, M Kostrzewa, T Maier… - Journal of clinical …, 2017 - Am Soc Microbiol
… pneumoniae and closely related Sreptococcusmitis species groupgenes have been
targeted in identification and phylogenetic studies, sometimes using an MLSA approach

Re-evaluation of the taxonomy of the Mitis group of the genus Streptococcus based on whole genome phylogenetic analyses, and proposed reclassification of Streptococcus dentisani as Streptococcus oralis subsp. dentisani …

A Jensen, CFP Scholz, M Kilian - International journal of …, 2016 - microbiologyresearch.org
… Furthermore, our data show that 16S rRNA gene sequences and ANI are unsuitable for
identifying and circumscribing new species of the Mitis group of the genus Streptococci. Based …