A novel solid self-nanoemulsifying drug delivery system (S-SNEDDS) for improved stability and oral bioavailability of an oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac …

KS Kim, ES Yang, DS Kim, DW Kim, HH Yoo… - Drug …, 2017 - Taylor & Francis
… a powerful oral drug delivery system for an oily drug, PLAG. … is still unsatisfactory, because
an oily drug hardly dissolves in the … of an oily drug to a practical solid pharmaceutical product. …

Effect of inorganic mesoporous carriers on 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol-loaded solid self-emulsifying drug delivery system: Physicochemical …

DS Kim, ES Yang, CS Yong, YS Youn, KT Oh… - Colloids and Surfaces B …, 2017 - Elsevier
The purpose of this study was to assess the impact of inorganic mesoporous carriers on the
physicochemical properties and oral bioavailability of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-…

[HTML][HTML] Comparison of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol-loaded self-emulsifying granule and solid self-nanoemulsifying drug delivery system: powder …

DS Kim, JS Kim, SJ Lim, JO Kim, CS Yong, HG Choi… - Pharmaceutics, 2019 - mdpi.com
… Owing to its oily properties, PLAG is practically insoluble in water, resulting in low … drug,
and liquid SMEDDS have poor flow ability [23]. The flow ability and bioavailability of oily drugs

Degradation kinetics study of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) by a validated stability-indicating RP-HPLC method

KS Kim, ES Yang, DS Kim, DW Kim, CS Yong… - … of Pharmaceutical and …, 2018 - Elsevier
… Moreover, PLAG is an oily drug which is poorly water-soluble. However, it is freely soluble
in acetonitrile and alcohol [16], [17]. Different mobile phase proportions of acetonitrile: …

[引用][C] A solid self-nanoemulsifying drug delivery system containing an oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol for improved stability and oral …

최한곤 - 2018 International Conference of The Korean Society …, 2018 - scholarworks.bwise.kr
ScholarWorks@Hanyang University ERICA Campus: A solid self-nanoemulsifying drug
delivery system containing an oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol for …

Development of PLAG-loaded solid SNEDDS formulation

ES Yang - 2017 - repository.hanyang.ac.kr
drug delivery system (SNEDDS) of water insoluble oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac–…
would be recommended as a powerful oral drug delivery system for an oily drug, PLAG. …

[HTML][HTML] Utilizing 505 (b)(2) Regulatory Pathway for New Drug Applications: An Overview on the Advanced Formulation Approach and Challenges

J Chen, Z Zhao, X Wang, J Huang - … and Opportunities in Drug …, 2023 - intechopen.com
drugs (Rx) to an over-the-counter (OTC), non-prescription product that differs from the OTC
monograph, and orphan drug … of older marketed drug products using innovative drug delivery …

[引用][C] … solid self-nanoemulsifying drug delivery system (S-SNEDDS) for improved stability and oral bioavailability of an oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac …

최한곤 - 2018 Spring International Convention of The …, 2018 - scholarworks.bwise.kr
ScholarWorks@Hanyang University ERICA Campus: A novel solid self-nanoemulsifying
drug delivery system (S-SNEDDS) for improved stability and oral bioavailability of an oily …

Effects of different physicochemical characteristics and supersaturation principle of solidified SNEDDS and surface-modified microspheres on the bioavailability of …

JE Choi, JS Kim, MJ Choi, K Baek, MR Woo… - International Journal of …, 2021 - Elsevier
… surfaces of drug, suggesting that hydrophilic carriers adhered to the hydrophobic drug. All …
However, it was considered “bad” when oily droplets aggregated, indicating the coalescence …

Comparison of three different aqueous microenvironments for enhancing oral bioavailability of sildenafil: solid self-nanoemulsifying drug delivery system, amorphous …

JS Kim, F Din, SM Lee, DS Kim, MR Woo… - International journal …, 2021 - Taylor & Francis
… decreased particle size compared to the drug powder. The crystalline microspheres exhibited
… Solid SNEDDS presented a smooth surface, assuming that the oily liquid was adsorbed to …