Effects of temperature, pH and counterions on the stability of peptide amphiphile nanofiber structures

AD Ozkan, AB Tekinay, MO Guler, ED Tekin - RSC advances, 2016 - pubs.rsc.org
… In this work, we used united-atom molecular dynamics simulations to understand the
effects … However, during the simulation of the PA2 nanofiber, there was an instability (disintegration …

Emergence of Dynamic Instability by Hybridizing Synthetic Self-Assembled Dipeptide Fibers with Surfactant Micelles

S Torigoe, K Nagao, R Kubota… - Journal of the American …, 2024 - ACS Publications
… Here, we report the emergence of dynamic instability through the hybridization of peptide-type
supramolecular nanofibers with surfactant micelles composed of sodium dodecyl sulfate (…

Stability of nanopeptides: structure and molecular exchange of self-assembled peptide fibers

N König, SM Szostak, JE Nielsen, M Dunbar… - ACS …, 2023 - ACS Publications
… a family of peptides that form beta-sheet nanofibers and … of the peptide molecules, we
performed molecular dynamics … generally suffer from intrinsic instability, molecular exchange, …

Investigating the stability of RADA16 peptide nanofibers using CD spectra

H Zarei, A Aramvash, MS Seyedkarimi - International Journal of Peptide …, 2019 - Springer
… However, it is still unclear in which conditions the peptide maintains … dynamic behavior of
RADA 16-I using circular dichroism, so as to monitor changes in conformation of the peptides

Nanofibers produced by electrospinning of ultrarigid polymer rods made from designed peptide bundlemers

K Kim, CJ Kloxin, JG Saven… - ACS Applied Materials & …, 2021 - ACS Publications
… Mechanical properties of electrospun nanofibers were measured using a dynamical
mechanical analyzer (RSA G2; TA Instruments) with a solid clamp in tension mode at room …

Mechanical properties of differentiating stem cells on peptide nanofibers

AE Topal, AB Tekinay, MO Guler, A Dana - Biophysical Journal, 2016 - cell.com
… In the case of flows resulting from a contractile instability, we propose a phase diagram of
3-dimensional cell shapes that encompasses nonpolarized spherical, elongated, as well as …

Short peptide nanofiber biomaterials ameliorate local hemostatic capacity of surgical materials and intraoperative hemostatic applications in clinics

Z Yang, L Chen, J Liu, H Zhuang, W Lin… - Advanced …, 2023 - Wiley Online Library
… on designing various peptide nanofiber biomaterial devices, [ … two decades, short peptide
nanofiber biomaterials have served … Moreover, the commercial peptide nanofiber formulations …

… Antimicrobial Biomaterials: Integrating an Enzyme Degradation-Resistant Sequence into Self-Assembled Nanosystems to Overcome Stability Limitations of Peptide …

W Yu, X Guo, Q Li, X Li, Y Wei, C Shao, L Zhang… - Advanced Fiber …, 2024 - Springer
… The proteolytic and physiological instability that primarily hampers their effectiveness [11,12,…
peptide nanofiber templates. The highly stable, multifunctional self-assembling short peptide

Controlled-alignment patterns of dipeptide micro-and nanofibers

X Liu, J Danglad-Flores, S Eickelmann, B Sun, J Hao… - ACS …, 2022 - ACS Publications
… This work also offers a simple approach to build peptide assemblies with highly ordered
2D structures and well-controlled morphologies, which may be used as various functional …

Protein-mimetic peptide nanofibers: Motif design, self-assembly synthesis, and sequence-specific biomedical applications

W Zhang, X Yu, Y Li, Z Su, KD Jandt, G Wei - Progress in Polymer Science, 2018 - Elsevier
peptide nanofibers may be constructed via entanglement and non-covalent binding
between peptide nanofibers. … dynamics (REMD) has been recently used for studying self-assembled …