[HTML][HTML] Targeting PI3K/AKT signaling pathway in obesity

MS Savova, LV Mihaylova, D Tews, M Wabitsch… - Biomedicine & …, 2023 - Elsevier
PI3K/AKT signaling pathway that target obesity management is the main objective of this
review. The PI3K/AKT pathway … the PI3K/AKT signaling is provided. Moreover, druggability of …

Research progress on the PI3K/AKT signaling pathway in gynecological cancer

X Shi, J Wang, Y Lei, C Cong… - Molecular medicine …, 2019 - spandidos-publications.com
… using molecular targets in the PI3K/AKT signaling pathway. In brief, the present review
analyzed the effects of the PI3K/AKT signaling pathway on certain gynecological cancer types. …

PI3k/AKT signaling pathway: Erythropoiesis and beyond

M Jafari, E Ghadami, T Dadkhah… - Journal of cellular …, 2019 - Wiley Online Library
… This process is regulated by several signaling pathways, … PI3K/AKT is one of the most
important pathways that control … In this review, we focus on the role of PI3K/AKT pathway in …

The PI3K/AKT signaling pathway in cancer: Molecular mechanisms and possible therapeutic interventions

MR Khezri, R Jafari, K Yousefi, NM Zolbanin - Experimental and molecular …, 2022 - Elsevier
… of signaling molecules that regulate PI3K/AKT pathway with … relationship between the PI3K/AKT
signaling pathway and factors … regulating this signaling pathway have been summarized. …

PI3K/AKT/mTOR signaling pathway in breast cancer: from molecular landscape to clinical aspects

D Miricescu, A Totan, II Stanescu-Spinu… - International journal of …, 2020 - mdpi.com
… Currently, clinical studies evaluate inhibitors of the PI3K/AKT/mTOR … AKT signaling pathway,
the factors that activate this protein kinase B, PI3K/AKT-breast cancer mutations, PI3K/AKT/…

Crosstalk between circRNAs and the PI3K/AKT signaling pathway in cancer progression

C Xue, G Li, J Lu, L Li - Signal transduction and targeted therapy, 2021 - nature.com
… The phosphoinositide 3-kinase (PI3K)/AKT signaling pathway … Emerging data suggest that
the circRNA/PI3K/AKT axis … circRNAs in the circRNA/PI3K/AKT axis is significantly associated …

[HTML][HTML] The PI3K/AKT/mTOR signaling pathway in osteoarthritis: a narrative review

K Sun, J Luo, J Guo, X Yao, X Jing, F Guo - Osteoarthritis and cartilage, 2020 - Elsevier
… Based on these reports, we focused on the PI3K/AKT/mTOR signaling pathway and … signaling
pathways. We also present an overview of therapeutic approaches for targeting PI3K/AKT/…

Role of PI3K/Akt signaling pathway in cardiac fibrosis

W Qin, L Cao, IY Massey - Molecular and cellular biochemistry, 2021 - Springer
… -3 kinase (PI3K)/Akt signaling pathway in the cardiac fibrosis. First, we … PI3K/Akt in the
development of cardiac fibrosis via showing the main downstream targets of the PI3K/Akt pathway. …

Role of the PI3K/AKT/mTOR signaling pathway in ovarian cancer: Biological and therapeutic significance

MK Ediriweera, KH Tennekoon… - Seminars in cancer …, 2019 - Elsevier
… and clinical data of PI3K/AKT/mTOR pathway inhibitors in OC, there … the importance of
PI3K/AKT/mTOR signaling pathway in OC … with several PI3K/AKT/mTOR pathway inhibitors in OC. …

Targeting PI3K/AKT/mTOR signaling pathway in breast cancer

H Li, L Prever, E Hirsch, F Gulluni - Cancers, 2021 - mdpi.com
PI3K signaling pathway plays an essential role in many cellular processes and is frequently
… role of the PI3K signaling pathway and the most recently developed PI3K-targeting breast …