… of the genetic underpinnings of cardiometabolic disease. Yet, … the populations who are most
affected by cardiometabolic … in a genomic region associated with a particular trait. Diverse …

… with cardiometabolic … and cardiometabolic traits in the Finnish population. We used
sensitive methods to identify and genotype 129,166 high-confidence SVs from deep whole-genome …

… studies in which genome-wide risk scores with correction for LD structure did not yield a
uniform improvement in predictive power across all traits and all populations evaluated in the …

… Here we take advantage of genome-wide data and a large … on 16 anthropometric and
cardiometabolic traits. By analysing … phenotypic variation for these traits in our population. We find …

… Overweight and obesity in the majority of the population operates as a prototypical common
complex disease. Early genome-wide studies that attempted discovery beyond candidate …

… genome sequencing in high-risk or susceptible populations.151 Furthermore, a potentially
productive and accurate prediction strategy for complex traits … poor cardiometabolic outcomes, …

… contributes to many cardiometabolic traits by modulating host … As a large-scale
population-based cohort with extensive clinical … between the gut microbiome and cardiometabolic …

… traits to determine whether they share genetic risk factors (pleiotropy). We used genome-wide …
from a population-based study which includes both related and unrelated individuals. …

… Among an approximately 680 known genome-wide association study (GWAS) loci for
cardio-metabolic traits, we identified 140 coincident cis-eQTLs at 109 GWAS loci, including 93 …

… The population included in the present study is the same that has been used in a previous
study of our group in which the risk of microalbuminuria was presented (Marrachelli VG, …