Oxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis

S Portal-Nunez, P Esbrit, MJ Alcaraz, R Largo - Biochemical pharmacology, 2016 - Elsevier
… Aging also interferes with epigenetic mechanisms such as activity of histone acetylases that
control … potential targets for the treatment of OA, a prevalent and therapeutic-orphan disease. …

Epigenetic mechanisms and potential therapeutic targets in stroke

KC Morris-Blanco, AK Chokkalla… - Journal of Cerebral …, 2022 - journals.sagepub.com
epigenetic factors as therapeutic targets and biomarkers for stroke. Epigenetic mechanisms
… both the translational potential of epigenetic enzymes as therapeutic targets for stroke, as …

[HTML][HTML] Novel epigenetic therapeutic strategies and targets in cancer

Q Babar, A Saeed, TA Tabish, S Pricl, H Townley… - … et Biophysica Acta (BBA …, 2022 - Elsevier
… be a key therapeutic target for cancer treatment … epigenetics in cancer therapy for
immuno-oncological complications are currently available - ranging from basic treatment to …

Epigenetic regulation in Alzheimer's disease: is it a potential therapeutic target?

F Coppedè - Expert Opinion on Therapeutic Targets, 2021 - Taylor & Francis
… This article examines the epigenetic modifications observed in AD tissues… changes in DNA
methylation and histone tail modifications, discussing their role as potential therapeutic targets

The role of selected epigenetic pathways in cardiovascular diseases as a potential therapeutic target

A Wołowiec, Ł Wołowiec, G Grześk, A Jaśniak… - International Journal of …, 2023 - mdpi.com
… targeted therapeutic interventions. The aim of the study was to present selected epigenetic
pathways, … diseases, and their potential as a therapeutic target in specific medical conditions. …

Epigenetic modifiers as potential therapeutic targets in diabetic kidney disease

JM Martinez-Moreno, M Fontecha-Barriuso… - International journal of …, 2020 - mdpi.com
Epigenetic regulators control gene expression and are potential therapeutic targets. There
… and the histone post-translational modifications—histone methylation, acetylation and …

Potential epigenetic-based therapeutic targets for glioma

L Zang, SM Kondengaden, F Che, L Wang… - Frontiers in Molecular …, 2018 - frontiersin.org
changes have become new targets in the treatment of glioma. In this review, we present a
summary of the potential therapeutic targets … We further illustrate how epigenetic mechanisms …

The contribution and therapeutic potential of epigenetic modifications in Alzheimer's disease

IC Wood - Frontiers in neuroscience, 2018 - frontiersin.org
… ageing correlating with the timing of epigenetic changes occurring at a younger age in …
epigenetic changes may contribute to disease pathology. Exactly how epigenetic modifications

Epigenetic modification and therapeutic targets of diabetes mellitus

R Singh, S Chandel, D Dey, A Ghosh, S Roy… - Bioscience …, 2020 - portlandpress.com
… of new therapeutic targets. In this review, we discuss the possible epigenetic changes and
… We highlight the important epigenetic and non-epigenetic therapeutic targets involved in the …

Histone deacetylases function as novel potential therapeutic targets for cancer

H Zhang, YP Shang, H Chen, J Li - Hepatology Research, 2017 - Wiley Online Library
… to indicate that changes in epigenetic modifications of DNA and histones and changes in …
following liver transplantation and be a potential therapeutic target.37 Histone deacetylase 3 …