Base editing: precision chemistry on the genome and transcriptome of living cells
… Base editing is a newer genome-editing approach that … precise point mutations in genomic
DNA and RNA, highlight recent developments that expand the scope, specificity, precision …
DNA and RNA, highlight recent developments that expand the scope, specificity, precision …
Publisher Correction: Base editing: precision chemistry on the genome and transcriptome of living cells.
HA Rees, DR Liu - Nature Reviews. Genetics, 2018 - europepmc.org
The originally published article contained errors in reference numbering throughout table 1 (DNA
base editors and their approximate editing windows) due to the unintended …
base editors and their approximate editing windows) due to the unintended …
Implementation of whole-genome and transcriptome sequencing into clinical cancer care
E Cuppen, O Elemento, R Rosenquist, S Nikic… - JCO Precision …, 2022 - ascopubs.org
… How can whole-genome transcriptome sequencing (WGTS) be integrated into health care
systems to replace the standard of care for oncology? A panel of 25 global experts in oncology…
systems to replace the standard of care for oncology? A panel of 25 global experts in oncology…
[HTML][HTML] International standards for genomes, transcriptomes, and metagenomes
CE Mason, E Afshinnekoo, S Tighe, S Wu… - Journal of Biomolecular …, 2017 - ncbi.nlm.nih.gov
… in genomics, including whole genomes, transcriptomes, mixed genomic samples (… ,
which will be essential for robust approaches in clinical genomics and precision medicine. …
which will be essential for robust approaches in clinical genomics and precision medicine. …
Reviving the transcriptome studies: an insight into the emergence of single-molecule transcriptome sequencing
… end sites, and providing precise strand orientation to single exons … genome can be used
to improve or add de novo structural and functional annotation to a genome, improve genome …
to improve or add de novo structural and functional annotation to a genome, improve genome …
Comprehensive assessments of RNA-seq by the SEQC consortium: FDA-led efforts advance precision medicine
… For this study, 27 chemical compounds were selected to … transcriptome was adopted as the
gene model for data processing with UCSC rat genome rn4 as the reference genome. In total, …
gene model for data processing with UCSC rat genome rn4 as the reference genome. In total, …
[HTML][HTML] A study protocol for validation and implementation of whole-genome and-transcriptome sequencing as a comprehensive precision diagnostic test in acute …
E Berglund, G Barbany, C Orsmark-Pietras… - Frontiers in …, 2022 - frontiersin.org
… genomic information, have become the focal point of research interest as novel techniques
that can support precision … comprehensive genomic profiling for precision diagnostics. …
that can support precision … comprehensive genomic profiling for precision diagnostics. …
Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences
C Manzoni, DA Kia, J Vandrovcova… - Briefings in …, 2018 - academic.oup.com
… systems and eventually the development of successful precision medicine. This review
cuts across the boundaries between genomics, transcriptomics and proteomics, summarizing …
cuts across the boundaries between genomics, transcriptomics and proteomics, summarizing …
The transcriptomic toolbox: resources for interpreting large gene expression data within a precision medicine context for metabolic disease atherosclerosis
C Marín de Evsikova, ID Raplee, J Lockhart… - Journal of Personalized …, 2019 - mdpi.com
… The ongoing NHLBI TOPmed (Trans-omics for precision medicine) effort to generate ~150,000
individual genomes’ sequences and ~50,000 transcriptomes for the most prevalent …
individual genomes’ sequences and ~50,000 transcriptomes for the most prevalent …
Machine learning based toxicity prediction: from chemical structural description to transcriptome analysis
Y Wu, G Wang - International journal of molecular sciences, 2018 - mdpi.com
… Whole genome expression, or transcriptome … genome expression of cultured human cells
of a specific type by adding a test drug to the culture. By analyzing changes in the transcriptome…
of a specific type by adding a test drug to the culture. By analyzing changes in the transcriptome…
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