[HTML][HTML] Molecular and functional imaging in cancer-targeted therapy: current applications and future directions

JW Bai, SQ Qiu, GJ Zhang - Signal Transduction and Targeted Therapy, 2023 - nature.com
targeted cell signaling pathways, various molecular imaging … Moreover, the application of
molecular imaging for evaluating … imaging in evaluating the sensitivity to targeted therapy with …

Upregulation of key molecules for targeted imaging and therapy

VF Taelman, P Radojewski, N Marincek… - Journal of Nuclear …, 2016 - Soc Nuclear Med
… Then, we assessed sstr 2 expression using the primary sstr 2 -specific antibody UMB-1 and
a secondary antibody goat antirabbit IgG horseradish peroxidase conjugate, by adding the …

[HTML][HTML] Magnetic iron oxide nanoparticles for imaging, targeting and treatment of primary and metastatic tumors of the brain

LL Israel, A Galstyan, E Holler, JY Ljubimova - Journal of Controlled …, 2020 - Elsevier
imaging or therapy, they have attractive features for brain delivery. However, the greatest
limitations for the use of MRI/MPI for imaging … for targeting, imaging and therapy of primary and …

[HTML][HTML] Targeting copper in cancer imaging and therapy: a new theragnostic agent

G Capriotti, A Piccardo, E Giovannelli… - Journal of Clinical …, 2022 - mdpi.com
… 64 Cu uptake in peripheral large primary lung cancer lesion on PET/CT images, similar to
FDG uptake. High uptake of 64 Cu was detected in 36% of primary tumors and 27% of nodal …

Bone-targeted imaging and radionuclide therapy in prostate cancer

AH Iagaru, E Mittra, PM Colletti… - Journal of Nuclear …, 2016 - Soc Nuclear Med
… Advancing soft-tissue disease was the primary reason for the cessation of therapy. Adverse
events were mild and manageable. A decline in the serum alkaline phosphatase level was …

Applications of pHLIP technology for cancer imaging and therapy

LC Wyatt, JS Lewis, OA Andreev, YK Reshetnyak… - Trends in …, 2017 - cell.com
… pHLIP ® s target cancer cells in primary tumors as well as metastases based on the acidic
… Peptides of the pHLIP family share the same features in their primary sequences (Figure I) …

[HTML][HTML] Fluorescent imaging for cancer therapy and cancer gene therapy

Y Woo, S Chaurasiya, M O'Leary, E Han… - Molecular Therapy …, 2021 - cell.com
… same targets may also be exploited for optical imaging of … , fluorescence imaging (FI) and
bioluminescence imaging (BLI) … , and discrimination between primary and secondary effects of …

Multiplexed imaging for diagnosis and therapy

K Heinzmann, LM Carter, JS Lewis… - Nature Biomedical …, 2017 - nature.com
… guide therapeutic options 162 , and the addition of other imagingtargets and the early
objective response for both primary … breast-cancer patients receiving hormonal therapy 163 . This …

Targeting HER2 in nuclear medicine for imaging and therapy

AVF Massicano, BV Marquez-Nostra… - … Imaging, 2018 - journals.sagepub.com
… expression is the key for the success of HER2-targeted therapy. At present, there are 2 types
of … by dissemination of cancer cells from the primary lesion to distant organs. Many protocols …

Targeting fibronectin for cancer imaging and therapy

Z Han, ZR Lu - Journal of Materials Chemistry B, 2017 - pubs.rsc.org
… As shown in this study, metastatic tumors had much higher FN expression than the primary
tumor, enabling sufficient binding of the contrast agent in micrometastases for sensitive …