The role of haptoglobin and hemopexin in the prevention of delayed cerebral ischaemia after aneurysmal subarachnoid haemorrhage: a review of current literature

S Griffiths, J Clark, AA Adamides, J Ziogas - Neurosurgical Review, 2020 - Springer
… This process occurs after subarachnoid haemorrhage with free Hb and Hb breakdown
products in the subarachnoid space and brain parenchyma, driving oxidative stress and …

Effect of cerebrospinal fluid drainage on clinical outcomes following aneurysmal subarachnoid hemorrhage

LC Ascanio, R Gupta, Y Tachie-Baffour, K Chida… - Journal of Clinical …, 2022 - Elsevier
Objectives We study the relationship between external ventricular drainage (EVD) of
cerebrospinal fluid output and functional outcomes in patients with aneurysmal subarachnoid

[HTML][HTML] The role of the glycocalyx in the pathophysiology of subarachnoid hemorrhage-induced delayed cerebral ischemia

H Schenck, E Netti, O Teernstra, I De Ridder… - Frontiers in Cell and …, 2021 - frontiersin.org
Products of RBC lysis activate microglia, which in turn release additional cytokines. Activated
neutrophils and macrophages entering the subarachnoid space … Any product that may be …

[HTML][HTML] Lessons for the pathogenesis of vasospasm from a patient with sickle cell disease, moyamoya disease, subarachnoid hemorrhage, and 1 month of persistent …

WD Haselden, PJ Drew, EW Church - Journal of Neurosurgery: Case …, 2022 - thejns.org
… for tracking hemolysis in patients with concurrent hemolytic states. … of the breakdown products
of the SAH hematoma, … Haptoglobin administration into the subarachnoid space prevents …

Intraventricular hemorrhage: the role of blood components in secondary injury and hydrocephalus

T Garton, RF Keep, DA Wilkinson, JM Strahle… - Translational stroke …, 2016 - Springer
… hemoglobin following hemolysis after … subarachnoid fibrosis in chronic hydrocephalus [31].
Thus, there is considerable evidence that hemoglobin and hemoglobin degradation products

The fate of erythrocytes after cerebral hemorrhage

F Xia, RF Keep, F Ye, KG Holste, S Wan, G Xi… - Translational stroke …, 2022 - Springer
… Another method for examining erythrolysis is detection of erythrocyte degradation products
… With CSF circulation, drugs can directly reach the blood in the subarachnoid space. This …

[HTML][HTML] Role of damage associated molecular pattern molecules (DAMPs) in aneurysmal subarachnoid hemorrhage (aSAH)

SR Chaudhry, A Hafez, B Rezai Jahromi… - International journal of …, 2018 - mdpi.com
… or blood in the subarachnoid space indicated a common … So, hemoglobin and its degradation
products act as DAMPs … events triggered by subarachnoid blood hemolysis to prevent …

Characterization of the ionic profile of the extracellular space of the injured and ischemic brain: a microdialysis study

T Martínez-Valverde, A Sánchez-Guerrero… - Journal of …, 2017 - liebertpub.com
… TBI and aneurysmal subarachnoid hemorrhage who are comatose.In a report in the … has
a hemorrhagic component, the hemolysis contributes to the increase of the total K+ content. …

[HTML][HTML] Impaired microcirculation after subarachnoid hemorrhage in an in vivo animal model

KC Wang, SC Tang, JE Lee, JC Tsai, DM Lai… - Scientific Reports, 2018 - nature.com
… (A) Red blood cells were seen in the subarachnoid space (arrowhead) in the rat SAH model.
Diffuse thrombosis of small vessels beneath the cortex (black arrow) was demonstrated by …

Ferritin and neurotoxicity: a contributor to deleterious outcomes for subarachnoid hemorrhage

EJ Panther, R Zelmanovich, J Hernandez… - European …, 2022 - karger.com
Subarachnoid hemorrhage (SAH) causes hemolysis of erythrocytes leading to the release
… versus a measure of blood in the subarachnoid space, and serves as a key protein in SAH …