Background Inflammatory mechanism has been implicated in delayed cerebral ischemia (DCI)
and poor functional outcomes after subarachnoid hemorrhage (SAH). Identification of …

The major fluid compartments of the body are the intracellular compartment and the extracellular
compartment, which is subdivided into intravascular and interstitial spaces. The volume …

… was broadly fenestrated into the subarachnoid space, and the … Blood hemolysis initiates the
inflammatory response necessary … in any of the products or devices mentioned in this article. …

… Although it is unclear how blood constituents or breakdown products of blood cells can affect
… The thin membrane between the subdural space and subarachnoid space may allow rapid …

Intracerebral hemorrhage (ICH) is a severe type of stroke with high mortality and morbidity
rates. 1 Annually, in the United States, ICH affects approximately 80,000 patients, leading to …

… It has been shown in rats that accumulation of the hemolysis products hemoglobin and K
+ in the subarachnoid space can induce spreading ischemia—an inverse hemodynamic …

… Hemoglobin, its degradation products and erythrocytes can … The acute effects of subarachnoid
blood and the transient … immune cell access to the subarachnoid space [14]. SAH has a …

… , erythrocytes in the subarachnoid space lyse and liberate free … This approach is prone to
in-vitro hemolysis if the sample is not … Any product that may be evaluated in this article, or claim …

Secondary brain injury (SBI) occurs with a lag of several days post-bleeding in patients with
aneurysmal subarachnoid hemorrhage (aSAH) and is a strong contributor to mortality and …

… substitution fluids, we established a subarachnoid space occupying rat model that exactly
mimicked … Any product that may be evaluated in this article, or claim that may be made by its …