Parthanatos and its associated components: promising therapeutic targets for cancer

Y Zhou, L Liu, S Tao, Y Yao, Y Wang, Q Wei… - Pharmacological …, 2021 - Elsevier
… the parthanatos cascade represent promising therapeutic targets for cancer therapy. In …
promise targeted therapy of parthanatos and its associated components holds for cancer therapy. …

[HTML][HTML] Promising therapeutic targets for treatment of rheumatoid arthritis

J Huang, X Fu, X Chen, Z Li, Y Huang… - Frontiers in …, 2021 - frontiersin.org
… are potential and promising therapeutics for further research. Epigenetic Targets for Treatment
of … , JQ1, suggesting that this family of proteins may be promising therapeutic targets (191). …

[HTML][HTML] A comprehensive review on MAPK: a promising therapeutic target in cancer

C Braicu, M Buse, C Busuioc, R Drula, D Gulei… - Cancers, 2019 - mdpi.com
The mitogen-activated protein kinase (MAPK) pathway is an important bridge in the switch
from extracellular signals to intracellular responses. Alterations of signaling cascades are …

[HTML][HTML] miRNA: a promising therapeutic target in cancer

A Menon, N Abd-Aziz, K Khalid, CL Poh… - International journal of …, 2022 - mdpi.com
… Patent Updates for miRNA in Cancer Therapy Various miRNAs appear to be promising
therapeutic targets from a scientific perspective [191]. As seen by the sharp rise in the number of …

S1PR1 as a novel promising therapeutic target in cancer therapy

N Rostami, A Nikkhoo, A Ajjoolabady, G Azizi… - … diagnosis & therapy, 2019 - Springer
… can be considered as potential anti-tumor therapeutic targets, alone or in combination therapies.
… the potential use of S1P signaling modulators as therapeutic targets in cancer therapy. …

MiR-138: A promising therapeutic target for cancer

HH Sha, DD Wang, D Chen, SW Liu, Z Wang… - Tumor …, 2017 - journals.sagepub.com
MicroRNAs are small noncoding RNAs which regulate gene expressions at post-transcriptional
level by binding to the 3′-untranslated region of target messenger RNAs. Growing …

Toll-like receptors: promising therapeutic targets for inflammatory diseases

A Achek, D Yesudhas, S Choi - Archives of pharmacal research, 2016 - Springer
… In this review, we discuss the emerging role of TLRs in the pathogenesis of inflammatory
diseases and how targeting of TLRs offers a promising therapeutic strategy for the prevention …

[HTML][HTML] Update on FXR biology: promising therapeutic target?

CY Han - International journal of molecular sciences, 2018 - mdpi.com
… Thus, FXR has been identified as a promising therapeutic target for the management of
liver and/or metabolic diseases, allowing the pharmacological approaches to develop FXR …

[HTML][HTML] P-TEFb as a promising therapeutic target

K Fujinaga - Molecules, 2020 - mdpi.com
… P-TEFb is now recognized as an attractive and promising therapeutic target for
inflammation/autoimmune diseases, cardiac hypertrophy, cancer, infectious diseases, etc. In this …

[HTML][HTML] Aurora-A kinase as a promising therapeutic target in cancer

AB D'Assoro, T Haddad, E Galanis - Frontiers in oncology, 2016 - frontiersin.org
Mammalian Aurora family of serine/threonine kinases are master regulators of mitotic progression
and are frequently overexpressed in human cancers. Among the three members of the …