… different developmental stages. In this Review, we discuss the mechanisms and functions
of DNA methylation and demethylation in both mice and humans at CpG-rich promoters, gene …

… role of DNA methylation when present at promoter or … DNA methylation and its oxidised
forms 5hmC and 5-formylcytosine (5fC) in gametes and early mouse embryos and by methylation …

… We plotted the DNA methylation levels of promoters and genic regions for each … early mouse
embryogenesis 13 . Our data also showed that genes exhibiting hypomethylated promoters …

… We establish that DNA methylation of CpG-island promoters is a primary and causal silencing
mechanism for restricting ectopic expression of a large panel of germline genes. While we …

… methylation levels associated with the Gtl2 promoter … methylation dynamics during mouse
development. We show that unlike the deleterious effects of loss of parent-specific methylation …

… early embryo and the germline were likely undergoing dynamic DNA methylation changes.
… The DNA methylation from the ICR spreads into the H19 promoter, silencing H19 expression […

… promoter regions, are usually devoid of methylation [2]. DNA methylation is essential for
mammalian development … Aberrant DNA methylation patterns and mutations of genes encoding …

… Similar to measurements of DNA methylation profiles at promoters and enhancers, we
find that DNMT3A2 and DNMT3B1 are preferentially bound to silent promoters and de novo …

… classes of promoters. Proc Natl Acad Sci USA, 103:1412-1417.). Methylation of CGIs of a
promoter … On the other hand, the promoter regions of transcribed genes have CGIs devoid of …

… alters the genome-wide DNA methylation erasure process in mouse early pre-implantation
embryos. It is … on DNA methylation re-establishment in later stages of embryo development. …