… trial results for erlotinib and gefitinib led to differences in regulatory policy, no head-to-head
randomised controlled trials … initiated a randomised controlled trial of erlotinib vs gefitinib in …

… of EGFR TKIs; instead, we have included only randomized controlled trials that compared
EGFR … This is because randomized controlled trials have a more stringent and consistent study …

… As mentioned above, both randomized controlled trials and cohort studies were included
in this systematic review. The risk of bias in randomized controlled trials was assessed using …

… revealed superior PFS with osimertinib compared with first-generation EGFR TKIs (erlotinib
or gefitinib), and osimertinib has become the preferred first-line therapy. Consequently, there …

… Gefitinib was proven to be the better choice for advanced NSCLC, with equal antitumor …
AEs compared with erlotinib. Further large-scale, well-designed randomized controlled trials are …

… This study aimed to investigate the noninferiority of gefitinib compared with erlotinib. The
primary … On the basis of these factors, we established our trial as a noninferiority clinical trial. …

… study was a three-arm randomized open-label phase II study … and gefitinib to either pemetrexed
plus carboplatin or gefitinib alone … -2 study, intercalating chemotherapy with erlotinib.23 …

… clinical trials comparing the success rate of gefitinib, erlotinib and icotinib have been reported.
In the current study, … The quality of randomized controlled trials from the Cochrane network …

… Clinical studies have gradually demonstrated that activating … Gefitinib and erlotinib, both
regarded as first-generation EGFR… and dacomitinib improved PFS compared to gefitinib [58,59]; …

… compared with erlotinib, gefitinib is more suitable for treating advanced NSCLC in East
Asian patients. Further large-scale, well-designed randomized controlled trials are warranted to …