[HTML][HTML] Gefitinib provides similar effectiveness and improved safety than erlotinib for east Asian populations with advanced non–small cell lung cancer: a meta …
W Zhang, Y Wei, D Yu, J Xu, J Peng - BMC cancer, 2018 - Springer
… compared with erlotinib, gefitinib is more suitable for treating advanced NSCLC in East
Asian patients. Further large-scale, well-designed randomized controlled trials are warranted to …
Asian patients. Further large-scale, well-designed randomized controlled trials are warranted to …
[HTML][HTML] Comparison of the effectiveness of erlotinib, gefitinib, and afatinib for treatment of non‑small cell lung cancer in patients with common and rare EGFR gene …
P Krawczyk, DM Kowalski, R Ramlau… - Oncology …, 2017 - spandidos-publications.com
… Liang et al indicated that erlotinib, gefitinib, and afatinib have equivalent efficacy. This
meta-analysis included twelve phase III global clinical trials involving 1812 NSCLC patients with …
meta-analysis included twelve phase III global clinical trials involving 1812 NSCLC patients with …
[HTML][HTML] … beyond progression in patients with non-small-cell lung cancer following chemotherapy, erlotinib/gefitinib and afatinib: phase III randomized LUX-Lung 5 trial
… In conclusion, this study demonstrates that, in a clinically selected patient population, …
failed platinum-based chemotherapy, gefitinib/erlotinib and afatinib monotherapy improves PFS …
failed platinum-based chemotherapy, gefitinib/erlotinib and afatinib monotherapy improves PFS …
Gefitinib or Erlotinib vs Chemotherapy for EGFR Mutation-Positive Lung Cancer: Individual Patient Data Meta-Analysis of Overall Survival
CK Lee, L Davies, YL Wu, T Mitsudomi… - JNCI: Journal of the …, 2017 - academic.oup.com
… , there is no relative OS advantage with frontline gefitinib or erlotinib vs chemotherapy in
EGFR-mutated … Multiple randomized controlled trials (RCTs) have demonstrated improvement in …
EGFR-mutated … Multiple randomized controlled trials (RCTs) have demonstrated improvement in …
Erlotinib and the risk of oral cancer: the erlotinib prevention of oral cancer (EPOC) randomized clinical trial
WN William, V Papadimitrakopoulou, JJ Lee… - JAMA …, 2016 - jamanetwork.com
… This is also the first randomized clinical trial in the entire cancer prevention field to utilize
molecular risk assessment as a core selection strategy, thus attempting to develop a …
molecular risk assessment as a core selection strategy, thus attempting to develop a …
Combining Whole‐Brain Radiotherapy with Gefitinib/Erlotinib for Brain Metastases from Non‐Small‐Cell Lung Cancer: A Meta‐Analysis
M Zheng, H Sun, J Xu, G Yang, L Huo… - BioMed Research …, 2016 - Wiley Online Library
… controlled trials could be identified. Secondly, the small sample size of the included studies
… based on phase II trials, and more phase III randomized controlled trials are needed. Thirdly…
… based on phase II trials, and more phase III randomized controlled trials are needed. Thirdly…
[HTML][HTML] Dacomitinib versus erlotinib in patients with EGFR-mutated advanced nonsmall-cell lung cancer (NSCLC): pooled subset analyses from two randomized trials
SS Ramalingam, K O'Byrne, M Boyer, T Mok… - Annals of …, 2016 - Elsevier
… EGFR TKIs in gefitinib- and erlotinib-sensitive and -resistant preclinical models [6, 7]. In a …
comparison in randomized clinical trials is needed to address this important clinical issue. …
comparison in randomized clinical trials is needed to address this important clinical issue. …
… gefitinib as first-line treatment of patients with EGFR mutation-positive non-small-cell lung cancer (LUX-Lung 7): a phase 2B, open-label, randomised controlled trial
K Park, EH Tan, K O'Byrne, L Zhang, M Boyer… - The Lancet …, 2016 - thelancet.com
… A search of ClinicalTrials.gov showed that several randomised trials comparing EGFR tyrosine
kinase inhibitors are ongoing, including: a phase 2 trial comparing erlotinib and gefitinib (…
kinase inhibitors are ongoing, including: a phase 2 trial comparing erlotinib and gefitinib (…
[HTML][HTML] Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib
Y Kim, SH Lee, JS Ahn, MJ Ahn… - Cancer Research and …, 2019 - synapse.koreamed.org
… Our purpose of this study is to investigate how afatinib is used in real-world practice, and
whether it leads to different clinical outcomes compared with gefitinib or erlotinib. …
whether it leads to different clinical outcomes compared with gefitinib or erlotinib. …
[HTML][HTML] … of erlotinib 100 mg/d vs. gefitinib 250 mg/d in EGFR-mutated advanced non-small cell lung cancer (E100VG250): an open-label, randomized, phase 2 study
S Zhao, Z Zhang, W Fang, Y Zhang, Z Zhang… - Frontiers in …, 2020 - frontiersin.org
… randomized controlled trial to directly compare lower dose erlotinib with standard dose gefitinib
… Therefore, in Stage IV EGFR mutated NSCLC, this study showed that erlotinib 100 mg/d …
… Therefore, in Stage IV EGFR mutated NSCLC, this study showed that erlotinib 100 mg/d …