… DAMPs recognized by CD44 and P2X7 are hyaluronan and … The function of peritoneal
macrophages in sterile injury is … However, peritoneal macrophages recruited to sterile liver injury …

… The initiation of a sterile intrinsic inflammatory event induces HA accumulation at … injury has
been proposed to involve recognition of components of damaged cells by pattern recognition …

The glycosaminoglycan hyaluronan (HA) is a key component of the microenvironment
surrounding cells. In healthy tissues, HA molecules have extremely high molecular mass and …

… High molecular weight (HMW) hyaluronic acid (HA) has been studied in sterile injury models
… Instillation of hyaluronan reverses acid instillation injury to the mammalian blood gas barrier…

… From 1800 kDa down to 50 kDa, CD44 was the recognized receptor and pro-inflammatory …
vitro, mechanical injury induced to the cultures was very extensive. With a sterile tip, parallel …

… as in alveolar macrophages from injured lungs [25,31,32]. On the other hand, a hyaluronan
tetrasaccharide blocks TLR2 activation and protects against ischemic brain injury [33]. The …

… space are modified by injuries, they can become … of sterile injury, recognized by CD44
receptor and others [4,5]. Moreover, failure to remove HA degradative products from sites of injury …

… hyaluronan (HA) and the Receptor for Hyaluronan-Mediated Motility (RHAMM, CD168) have
been implicated in the response to acute lung injury… to injured WT animals, injured RHAMM …

… of sterile injury (19, 50), asthma (ova and cockroach allergen) (11, 51), ozone-induced airway
hyperreactivity (52), LPS-induced acute lung injury… is more efficiently recognized by the HA …

… , or hyaluronan (HA), is a nonsulfated glucosaminoglycan that has long been recognized for
… species generated during inflammation or tissue injury. Importantly, hyaluronidases consist …