[HTML][HTML] Sterile injury repair and adhesion formation at serosal surfaces
… DAMPs recognized by CD44 and P2X7 are hyaluronan and … The function of peritoneal
macrophages in sterile injury is … However, peritoneal macrophages recruited to sterile liver injury …
macrophages in sterile injury is … However, peritoneal macrophages recruited to sterile liver injury …
Emerging evidence for the essential role of hyaluronan in cutaneous biology
… The initiation of a sterile intrinsic inflammatory event induces HA accumulation at … injury has
been proposed to involve recognition of components of damaged cells by pattern recognition …
been proposed to involve recognition of components of damaged cells by pattern recognition …
Hyaluronan and hyaluronan fragments
MK Cowman - Advances in carbohydrate chemistry and biochemistry, 2017 - Elsevier
The glycosaminoglycan hyaluronan (HA) is a key component of the microenvironment
surrounding cells. In healthy tissues, HA molecules have extremely high molecular mass and …
surrounding cells. In healthy tissues, HA molecules have extremely high molecular mass and …
Therapeutic effects of hyaluronic acid in peritonitis-induced sepsis in mice
JH Lee, A Liu, JH Park, H Kato, Q Hao, X Zhang… - Shock, 2020 - journals.lww.com
… High molecular weight (HMW) hyaluronic acid (HA) has been studied in sterile injury models
… Instillation of hyaluronan reverses acid instillation injury to the mammalian blood gas barrier…
… Instillation of hyaluronan reverses acid instillation injury to the mammalian blood gas barrier…
Is molecular size a discriminating factor in hyaluronan interaction with human cells?
A D'Agostino, A Stellavato, L Corsuto, P Diana… - Carbohydrate …, 2017 - Elsevier
… From 1800 kDa down to 50 kDa, CD44 was the recognized receptor and pro-inflammatory …
vitro, mechanical injury induced to the cultures was very extensive. With a sterile tip, parallel …
vitro, mechanical injury induced to the cultures was very extensive. With a sterile tip, parallel …
Hyaluronan biology: A complex balancing act of structure, function, location and context
S Garantziotis, RC Savani - Matrix Biology, 2019 - Elsevier
… as in alveolar macrophages from injured lungs [25,31,32]. On the other hand, a hyaluronan
tetrasaccharide blocks TLR2 activation and protects against ischemic brain injury [33]. The …
tetrasaccharide blocks TLR2 activation and protects against ischemic brain injury [33]. The …
[HTML][HTML] Endogenously-produced hyaluronan and its potential to regulate the development of peritoneal adhesions
A Kocurkova, K Nesporova, M Sandanusova… - Biomolecules, 2021 - mdpi.com
… space are modified by injuries, they can become … of sterile injury, recognized by CD44
receptor and others [4,5]. Moreover, failure to remove HA degradative products from sites of injury …
receptor and others [4,5]. Moreover, failure to remove HA degradative products from sites of injury …
[HTML][HTML] The Receptor for Hyaluronan-Mediated Motility (CD168) promotes inflammation and fibrosis after acute lung injury
Z Cui, J Liao, N Cheong, C Longoria, G Cao… - Matrix Biology, 2019 - Elsevier
… hyaluronan (HA) and the Receptor for Hyaluronan-Mediated Motility (RHAMM, CD168) have
been implicated in the response to acute lung injury… to injured WT animals, injured RHAMM …
been implicated in the response to acute lung injury… to injured WT animals, injured RHAMM …
[HTML][HTML] Hyaluronan and its interactions with immune cells in the healthy and inflamed lung
… of sterile injury (19, 50), asthma (ova and cockroach allergen) (11, 51), ozone-induced airway
hyperreactivity (52), LPS-induced acute lung injury… is more efficiently recognized by the HA …
hyperreactivity (52), LPS-induced acute lung injury… is more efficiently recognized by the HA …
Hyaluronan in Adipose Tissue, Metabolic Inflammation, and Diabetes: Innocent Bystander or Guilty Party?
K Drygalski, S Lecoutre, K Clément, I Dugail - Diabetes, 2023 - Am Diabetes Assoc
… , or hyaluronan (HA), is a nonsulfated glucosaminoglycan that has long been recognized for
… species generated during inflammation or tissue injury. Importantly, hyaluronidases consist …
… species generated during inflammation or tissue injury. Importantly, hyaluronidases consist …