Improved abnormal Pap smear triage using cervical cancer biomarkers
JL Killeen, T Dye, C Grace… - Journal of lower genital …, 2014 - journals.lww.com
Objective The current system of Pap smear screening and management of abnormal
cytology has resulted in a marked reduction in invasive cervical cancer. Many women …
cytology has resulted in a marked reduction in invasive cervical cancer. Many women …
CINtec® PLUS dual immunostain: A triage tool for cervical pap smears with atypical squamous cells of undetermined significance and low grade squamous …
ASC and LSIL comprise the majority of abnormal Pap smears. Currently, high‐risk human
papillomavirus testing is utilized to triage women with ASC for colposcopy; however, no cost …
papillomavirus testing is utilized to triage women with ASC for colposcopy; however, no cost …
Performance of p16/Ki-67 immunostaining to detect cervical cancer precursors in a colposcopy referral population
N Wentzensen, L Schwartz, RE Zuna, K Smith… - Clinical Cancer …, 2012 - AACR
Purpose: Cytology-based screening has limited sensitivity to detect prevalent cervical
precancers. Human papilloma virus (HPV) DNA testing is highly sensitive and provides a …
precancers. Human papilloma virus (HPV) DNA testing is highly sensitive and provides a …
[HTML][HTML] Comparison of papanicolaou smear and human papillomavirus (HPV) test as cervical screening tools: can we rely on HPV test alone as a screening method …
M Kang, SY Ha, HY Cho, DH Chung… - … of pathology and …, 2020 - synapse.koreamed.org
Background The decrease in incidence of cervical dysplasia and carcinoma has not been as
dramatic as expected with the development of improved research tools and test methods …
dramatic as expected with the development of improved research tools and test methods …
Role of ancillary techniques in cervical biopsy and endocervical curettage specimens as follow-up to Papanicolaou test results indicating a diagnosis of atypical …
The Papanicolaou (PAP) test is widely used to screen for cervical cancer. All high-grade
lesions such as atypical squamous cells, cannot exclude high-grade squamous …
lesions such as atypical squamous cells, cannot exclude high-grade squamous …
Human papillomavirus testing and molecular markers of cervical dysplasia and carcinoma
D Dehn, KC Torkko, KR Shroyer - … International Journal of the …, 2007 - Wiley Online Library
Cervical cancer is the second most common cancer in women worldwide. Human
papillomavirus (HPV) is the etiologic agent for the vast majority of premalignant and …
papillomavirus (HPV) is the etiologic agent for the vast majority of premalignant and …
Performance of p16INK4a-cytology, HPV mRNA, and HPV DNA testing to identify high grade cervical dysplasia in women with abnormal screening results
M Reuschenbach, A Clad, C von Knebel Doeberitz… - Gynecologic …, 2010 - Elsevier
OBJECTIVE: The prognostic value of dysplastic lesions of the uterine cervix cannot be
adequately determined by Pap cytology alone. Detection of HPV DNA increases the …
adequately determined by Pap cytology alone. Detection of HPV DNA increases the …
[HTML][HTML] HPV L1 detection discriminates cervical precancer from transient HPV infection: a prospective international multicenter study
G Mehlhorn, E Obermann, G Negri, L Bubendorf… - Modern Pathology, 2013 - Elsevier
The benefits of cytology-based cervical cancer screening programs in reducing morbidity
and mortality are well recognized. Especially, overtreatment of human papillomavirus (HPV) …
and mortality are well recognized. Especially, overtreatment of human papillomavirus (HPV) …
p16/Ki-67 dual stain cytology for detection of cervical precancer in HPV-positive women
N Wentzensen, B Fetterman, PE Castle… - Journal of the …, 2015 - academic.oup.com
Abstract Background: Human papillomavirus (HPV)–based cervical cancer screening
requires triage markers to decide who should be referred to colposcopy. p16/Ki-67 dual …
requires triage markers to decide who should be referred to colposcopy. p16/Ki-67 dual …
Triaging Pap cytology negative, HPV positive cervical cancer screening results with p16/Ki-67 Dual-stained cytology
KU Petry, D Schmidt, S Scherbring, A Luyten… - Gynecologic …, 2011 - Elsevier
OBJECTIVE: Testing for human papillomavirus (HPV) has been shown to increase the
sensitivity and negative predictive value for detection of high-grade cervical intraepithelial …
sensitivity and negative predictive value for detection of high-grade cervical intraepithelial …